Effect of food on the pharmacokinetics of omeprazole pantoprazole and rabeprazole

机译：食物对奥美拉唑泮托拉唑和拉巴拉唑的药代动力学的影响

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摘要

Pharmacokinetic parameters for pantoprazole, rabeprazole, and omeprazole under fasting and fed conditions. Among 71 volunteers receiving omeprazole, 35 were the same subjects. Data are expressed as mean ± standard deviation. *p ≤ 0.05 vs. men

机译：禁食和喂养条件下Pantoprazole，Rabepazole和Omeprazole的药代动力学参数。在71个接受奥美拉唑的志愿者中，35名是相同的主题。数据表示为平均值±标准偏差。 *p≤0.05与男性

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期刊名称 BMC Pharmacology Toxicology
作者
Dolores Ochoa; Manuel Román; Teresa Cabaleiro; Miriam Saiz-Rodríguez; Gina Mejía; Francisco Abad-Santos;
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作者单位

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年(卷),期 2020(-1),-1
年度 2020
页码 -1
总页数 9
原文格式 PDF
正文语种
中图分类药学;
关键词

机译：质子泵抑制剂;食物;药代动力学;奥美拉唑;rabebazole;泮托拉唑;

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专利

1. Simultaneous estimation of four proton pump inhibitors--lansoprazole, omeprazole, pantoprazole and rabeprazole: development of a novel generic HPLC-UV method and its application to clinical pharmacokinetic study. [J] . Bharathi DV, Hotha KK, Jagadeesh B Biomedical Chromatography: An International Journal Devoted to Research in Chromatographic Methodologies and Their Applications in the Biosciences . 2009,第7期

机译：同时估算四种质子泵抑制剂兰索拉唑，奥美拉唑，pan托拉唑和雷贝拉唑：新型HPLC-UV方法的开发及其在临床药代动力学研究中的应用。
2. RP-HPLC Method for the Simultaneous Determination of Pantoprazole Sodium, Omeprazole, Rabeprazole Sodium, Lansoprazole, and Domperidone in Bulk and Pharmaceutical Dosage Form [J] . International Journal of Pharmaceutical Sciences Review and Research . 2015,第2期

机译：RP-HPLC法同时测定散装和药物剂型的Pan托拉唑钠，奥美拉唑，雷贝拉唑钠，兰索拉唑和多潘立酮
3. Normal and polar-organic-phase high-performance liquid chromatographic enantioresolution of omeprazole, rabeprazole, lansoprazole and pantoprazole using monochloro-methylated cellulose-based chiral stationary phase and determination of dexrabeprazole [J] . DixitS., DubeyR., BhushanR. Biomedical Chromatography: An International Journal Devoted to Research in Chromatographic Methodologies and Their Applications in the Biosciences . 2014,第1期

机译：单氯甲基化纤维素基手性固定相用于奥美拉唑，雷贝拉唑，兰索拉唑和pan托拉唑的正相和极性有机相高效液相色谱对映体测定和右旋贝拉唑
4. Pharmacokinetics evaluation of soft agglomerates containing enteric pantoprazole-loadedmicroparticles in dogs [C] . R. P. Raffin, S. E. Haas, L. M. Colomé, Annual meeting exposition of the Controlled Release Society . 2009

机译：犬肠溶性负载top托拉唑微粒的软团块的药代动力学评估
5. An Investigation into the Effect of Clinical States of Infection on Pharmacokinetics and Pharmacodynamics in Ruminant Food Animal Species [D] . Smith, Joseph Sameul. 2019

机译：对反刍食品动物物种临床感染临床态度对药代动力学和药效学的影响
6. Pharmacokinetics and effect on caffeine metabolism of the proton pump inhibitors omeprazole lansoprazole and pantoprazole [O] . Tommy Andersson, Johan Holmberg, Kerstin Röhss, 1998

机译：质子泵抑制剂奥美拉唑兰索拉唑和pan托拉唑的药代动力学及其对咖啡因代谢的影响
7. Improved HPLC Method for Determination of Four PPIs, Omeprazole, Pantoprazole, Lansoprazole and Rabeprazole in Human Plasma [O] . Maryam Noubarani, Fariborz Keyhanfar, Manijeh Motevalian, 2010

机译：改进的HPLC方法，用于测定四种PPI，Omeprazole，PantoPrazole，Lansoprazole和人血浆中的rabeprazole

Effect of food on the pharmacokinetics of omeprazole pantoprazole and rabeprazole

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