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Multiple cystic lung lesions and autoimmune thrombocytopaenia developing after chemotherapy for pulmonary indolent B-cell lymphoma with plasmacytic differentiation

机译:多种囊性肺病灶和自身免疫性血小板减少血小阴盆治疗肺惰性B细胞淋巴瘤的肺惰性B细胞淋巴瘤

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摘要

Among lung malignancies, primary pulmonary lymphoma is rare and many of them are indolent B-cell lymphomas. We describe a case of primary pulmonary indolent B-cell lymphoma with plasmacytic differentiation, which exacerbated with the manifestation of macroglobulinaemia and was successfully treated using chemotherapy. The patient subsequently developed pulmonary cysts and thrombocytopaenia due to autoimmune pathology and was successfully treated using prednisolone. This case suggests that in indolent B-cell lymphoma with plasmacytic differentiation, immunoglobulin M level should be carefully followed even if it is within the normal range at lymphoma onset. Additionally, new cystic pulmonary infiltrates that develop during the post-treatment follow-up of an indolent pulmonary B-cell lymphoma may indicate pulmonary lymphoma recurrence, but there is also a possibility of an immunological complication.
机译:在肺部恶性肿瘤中,初级肺淋巴瘤是罕见的,其中许多是惰性B细胞淋巴瘤。我们描述了具有浆性分化的初级肺惰性B细胞淋巴瘤的案例,其随着宏观球蛋白血症的表现而加剧,并使用化疗成功处理。由于自身免疫病理学,患者随后发育了肺囊肿和血小板减少症,并使用泼尼松成功处理。这种情况表明,在具有血浆分化的惰性B细胞淋巴瘤中,即使它在淋巴瘤发作的正常范围内,也应仔细遵循免疫球蛋白M水平。另外,在惰性肺B细胞淋巴瘤的后处理后发生的新囊性肺渗透可能表明肺淋巴瘤复发,但也有可能具有免疫复杂性的可能性。

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