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Bridging Computational Vaccinology and Vaccine Development Through Systematic Identification Characterization and Downselection of Conserved and Variable Circumsporozoite Protein CD4 T Cell Epitopes From Diverse Plasmodium falciparum Strains

机译：通过系统鉴定表征和缩小覆盆子菌蛋白CD4 T细胞表位的系统鉴定表征和缩小桥接计算疫苗疫苗和疫苗开发来自不同的疟原虫菌株

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期刊名称 Frontiers in Immunology
作者
Amy R. Noe; Frances E. Terry; Brian C. Schanen; Emily Sassano; Pooja Hindocha; Timothy W. Phares; Leonard Moise; Jayne M. Christen; Kenneth D. Tucker; Vinayaka Kotraiah; Donald R. Drake III; William D. Martin; Anne S. De Groot; Gabriel M. Gutierrez;
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作者单位

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年(卷),期 2021(-1),-1
年度 2021
页码 -1
总页数 14
原文格式 PDF
正文语种
中图分类免疫学;
关键词

机译：疟疾;CSP;

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专利

1. A CD4(+) T-cell immune response to a conserved epitope in the circumsporozoite protein correlates with protection from natural Plasmodium falciparum infection and disease. [J] . Reece WH, Pinder M, Gothard PK, Nature medicine . 2004,第4期

机译：对环子孢子蛋白中保守表位的CD4（+）T细胞免疫应答与天然恶性疟原虫感染和疾病的保护相关。
2. Binding of malaria T cell epitopes to DR and DQ molecules in vitro correlates with immunogenicity in vivo: identification of a universal T cell epitope in the Plasmodium falciparum circumsporozoite protein. [J] . Calvo Calle JM, Hammer J, Sinigaglia F, The Journal of Immunology: Official Journal of the American Association of Immunologists . 1997,第3期

机译：体外疟疾T细胞表位与DR和DQ分子的结合与体内免疫原性相关：恶性疟原虫环子孢子蛋白中通用T细胞表位的鉴定。
3. Binding of malaria T cell epitopes to DR and DQ molecules in vitro correlates with immunogenicity in vivo: identification of a universal T cell epitope in the Plasmodium falciparum circumsporozoite protein. [J] . J M Calvo-Calle, J Hammer, F Sinigaglia, The journal of immunology . 1997,第3期

机译：体外疟疾T细胞表位与DR和DQ分子的结合与体内免疫原性相关：恶性疟原虫环子孢子蛋白中通用T细胞表位的鉴定。
4. Variation in the Circumsporozoite Protein of Plasmodium falciparum: Implications for Vaccine Development. [D] . Gandhi, Kavita. 2013

机译：恶性疟原虫环子孢子蛋白的变异：对疫苗开发的影响。
5. Identification of Plasmodium falciparum circumsporozoite protein-specific CD8+ T cell epitopes in a malaria exposed population [O] . Kwadwo A. Kusi, Felix E. Aggor, Linda E. Amoah, 2020

机译：疟疾暴露人群中恶性疟原虫环子孢子蛋白特异性CD8 + T细胞表位的鉴定
6. Identification of minimal human MHC-restricted CD8+ T-cell epitopes within the Plasmodium falciparum circumsporozoite protein (CSP) [O] . Sedegah, Martha, Kim, Yohan, Ganeshan, Harini, 2013

机译：鉴定恶性疟原虫环子孢子蛋白（CSP）中最小的人类MHC限制性CD8 + T细胞表位
7. Characterization of Plasmodium falciparum Sporozoite Surface Protein 2(malaria/vaccine/thrombospondin related anonymous protein/T-cell Western blot/circumsporozoite protein) [R] . Rogers, W. O., Malik, A., Mellouk, S., 1992

机译：恶性疟原虫子孢子表面蛋白2的表征（疟疾/疫苗/血小板反应蛋白相关的匿名蛋白/ T细胞蛋白质印迹/环子孢子蛋白）

Bridging Computational Vaccinology and Vaccine Development Through Systematic Identification Characterization and Downselection of Conserved and Variable Circumsporozoite Protein CD4 T Cell Epitopes From Diverse Plasmodium falciparum Strains

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