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Shared Pheromonal Communication of Specific Fear Between Adult Sprague Dawley Rats

机译:成人Sprague Dawley大鼠特定恐惧的共享信息沟通

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摘要

Rats are highly social animals, and mainly communicate with one another in two ways: through ultrasonic vocalizations and pheromones. Most research on pheromones has been dedicated those regarding sexual behavior, but more recently pheromones which signal danger to conspecifics have been identified in rodents. In fact, rats are capable of communicating information regarding a specific fear to a companion with which they share a cage. If a rat is trained to associate a previously neutral odor with a foot shock and then pair housed with another rat, the companion will also display a fear response specific to the trained odor, despite never being shocked itself. This communication relies on pheromones; presenting soiled bedding from a shocked rat to an individually housed naïve rat produces the same fear response in the naïve rat. The current protocol describes how to produce this phenomenon in adult Sprague Dawley rats. It is simple and easily reproduced, requires minimal equipment, and may be completed within one week.
机译:大鼠是高度社交的动物,主要用两种方式互相沟通:通过超声声和信息素。关于信息素的大多数研究已经致力于有关性行为的研究,但最近的信息素是在啮齿动物中识别出对CINCIFIFICS的危险的信息。事实上,大鼠能够将关于特定恐惧的信息传达给他们共享笼子的伴侣。如果培训大鼠以将先前中性气味与脚休克联系起来,然后对另一只老鼠配对,伴侣也将显示特定于训练的气味的恐惧反应,尽管从未震惊本身。这种通信依赖于信息素;将震动的大鼠从震惊的大鼠呈现污染的床上用品,在幼稚大鼠中产生相同的恐惧反应。目前的协议描述了如何在成人Sprague Dawley大鼠中产生这种现象。它简单且易于复制,需要最小的设备,并且可以在一周内完成。

著录项

  • 期刊名称 Bio-protocol
  • 作者单位
  • 年(卷),期 2020(10),6
  • 年度 2020
  • 页码 e3564
  • 总页数 11
  • 原文格式 PDF
  • 正文语种
  • 中图分类 生物学;
  • 关键词

    机译:报警信息素;调节;恐惧;休克;配对;冻结;嗅觉;气味;

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