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Structure of the gene complementing uvr-402 in Streptococcus pneumoniae: homology with Escherichia coli uvrB and the homologous gene in Micrococcus luteus.

机译：肺炎链球菌中补充uvr-402的基因的结构：与大肠杆菌uvrB的同源性和黄Micro微球菌的同源基因。

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摘要

The repair ability for UV-induced damage observed for Streptococcus pneumoniae proceeds through a system similar to the Uvr-dependent system in Escherichia coli. The DNA sequence of a gene complementing uvr-402, a mutation conferring UV sensitivity, was determined. Alignments of the deduced amino acid sequence revealed an extensive sequence homology of 55% with the UvrB protein of E. coli and 59% with the UvrB-homologous protein of Micrococcus luteus. Nucleotide-binding site consensus was observed. The high conservation of the uvrB-like gene among these three species suggests that the role of the UvrB protein and excision repair in general might be very important for cell survival.

机译：对肺炎链球菌观察到的紫外线诱导的损伤的修复能力是通过类似于大肠杆菌中依赖Uvr的系统进行的。确定了补充uvr-402的基因的DNA序列，该基因赋予UV敏感性。推导的氨基酸序列的比对揭示了与大肠杆菌的UvrB蛋白的55％的广泛序列同源性和与黄曲霉的UvrB同源的蛋白的59％的广泛序列同源性。观察到核苷酸结合位点共有。这三个物种中的uvrB样基因的高度保守性表明，UvrB蛋白的作用和切除修复通常可能对细胞存活非常重要。

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期刊名称 Journal of Bacteriology
作者
N Sicard; J Oreglia; A M Estevenon;
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年(卷),期 1992(174),7
年度 1992
页码 2412–2415
总页数 4
原文格式 PDF
正文语种
中图分类微生物学;
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专利

1. Structure of the uvrB gene of Escherichia coli. Homology with other DNA repair enzymes and characterization of the uvrB5 mutation [J] . A.P. Barbeiro, C. Backendorf, H. Spaink, Nucleic acids research . 1986,第7期

机译：大肠杆菌uvrB基因的结构。与其他DNA修复酶的同源性和uvrB5突变的特征
2. Nucleotide sequences of genes encoding penicillin-binding proteins from Streptococcus pneumoniae and Streptococcus oralis with high homology to Escherichia coli penicillin-binding proteins 1a and 1b. [J] . C Martin, T Briese, R Hakenbeck Journal of bacteriology . 1992,第13期

机译：与肺炎链球菌和青霉素结合蛋白1a和1b具有高度同源性的编码来自肺炎链球菌和口腔链球菌的青霉素结合蛋白的基因的核苷酸序列。
3. Nucleotide sequence of the hexA gene for DNA mismatch repair in Streptococcus pneumoniae and homology of hexA to mutS of Escherichia coli and Salmonella typhimurium. [J] . S D Priebe, S M Hadi, B Greenberg, Journal of bacteriology . 1988,第1期

机译：用于肺炎链球菌DNA错配修复的hexA基因的核苷酸序列，以及hexA与大肠杆菌和鼠伤寒沙门氏菌mutS的同源性。
4. Optimization of expression conditions of dhaT gene from Klebsiella pneumoniae in Escherichia coli using uniform design [C] . China-Japan-Korea Joint Symposium on Enzyme Engineering . 2004

机译：均匀设计法优化肺炎克雷伯菌dhaT基因在大肠杆菌中的表达条件。
5. The effects of low-shear modeled microgravity on Streptococcus pneumoniae and adherent-invasive Escherichia coli. [D] . Allen, Christopher A. 2007

机译：低剪切模拟微重力对肺炎链球菌和黏附侵袭性大肠杆菌的影响。
6. Structure of the uvrB gene of Escherichia coli. Homology with other DNA repair enzymes and characterization of the uvrB5 mutation. [O] . C Backendorf, H Spaink, A P Barbeiro, 1986

机译：大肠杆菌uvrB基因的结构。与其他DNA修复酶的同源性和uvrB5突变的特征。
7. Structure of the gene complementing uvr-402 in Streptococcus pneumoniae: homology with Escherichia coli uvrB and the homologous gene in Micrococcus luteus. [O] . Sicard, N, Oreglia, J, Estevenon, A M 1992

机译：肺炎链球菌中补充uvr-402的基因的结构：与大肠杆菌uvrB的同源性和黄and微球菌的同源基因。

Structure of the gene complementing uvr-402 in Streptococcus pneumoniae: homology with Escherichia coli uvrB and the homologous gene in Micrococcus luteus.

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