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Phytochemicals of Aristolochia tagala and Curcuma caesia exert anticancer effect by tumor necrosis factor-α-mediated decrease in nuclear factor kappaB binding activity

机译：塔氏马兜铃和莪术的植物化学物质通过肿瘤坏死因子-α介导的核因子κB结合活性的降低发挥抗癌作用

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Rationale:The active compounds or metabolites of herbal plants exert a definite physiological action on the human body and thus are widely used in human therapy for various diseases including cancer. Previous studies by our group have reported the anticarcinogenic properties of the two herbal plants extracts (HPE) of Aristolochia tagala (AT) Cham. and Curcuma caesia (CC) Roxb. in diethylnitrosamine-induced mouse liver cancer in vivo. The anticarcinogenic properties of these extracts may be due to the active compounds present in them.

机译：原理：草药植物的活性化合物或代谢产物对人体具有确定的生理作用，因此被广泛用于人类治疗包括癌症在内的各种疾病。我们小组先前的研究已经报道了两种马兜铃（Aristolochia tagala（AT）Cham）草药提取物（HPE）的抗癌特性。和Curcuma caesia（CC）Roxb。在二乙基亚硝胺诱导的小鼠肝癌体内。这些提取物的抗癌特性可能归因于其中存在的活性化合物。

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期刊名称 Journal of Basic and Clinical Pharmacy
作者
Khetbadei Lysinia Hynniewta Hadem; Rajeshwar Nath Sharan; Lakhan Kma;
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作者单位

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年(卷),期 2015(7),1
年度 2015
页码 1–1
总页数 11
原文格式 PDF
正文语种
中图分类药学;
关键词
Antioxidant Aristolochia tagala Curcuma caesia diethylnitrosamine high performance thin layer chromatography nuclear factor kappaB tumor necrosis factor-α;

机译：抗氧化剂;塔氏马兜铃;莪术;二乙基亚硝胺;高效薄层色谱;核因子κB;肿瘤坏死因子-α;

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专利

1. Phytochemicals of Aristolochia tagala and Curcuma caesia exert anticancer effect by tumor necrosis factor-α-mediated decrease in nuclear factor kappaB binding activity [J] . Khetbadei Lysinia Hynniewta Hadem, Rajeshwar Nath Sharan, Lakhan Kma Journal of Basic and Clinical Pharmacy . 2016,第1期

机译：塔氏马兜铃和莪术的植物化学物质通过肿瘤坏死因子-α介导的核因子κB结合活性的降低发挥抗癌作用
2. Combined treatment with verrucarin A and tumor necrosis factor-α sensitizes apoptosis by overexpression of nuclear factor-kappaB-mediated Fas [J] . Rajapaksha Gedara Prasad Tharanga Jayasooriya, Dong-Oh Moon, Sang Rul Park, Environmental toxicology and pharmacology . 2013,第2期

机译：Verrucarin A和肿瘤坏死因子-α的联合治疗通过核因子-κB介导的Fas的过度表达来增强细胞凋亡
3. Atorvastatin exerts anti-nociceptive activity and decreases serum levels of high-sensitivity C-reactive protein and tumor necrosis factor-α in a rat endometriosis model. [J] . Yavuz Simsek, Mehmet Gul, Ercan Yilmaz, Archives of gynecology and obstetrics. . 2014,第5期

机译：阿托伐他汀在大鼠子宫内膜异位症模型中具有抗伤害感受活性，并降低血清高敏C反应蛋白和肿瘤坏死因子-α的水平。
4. Orthopedic Implant Particle-Induced Tumor Necrosis Factor-a Production in Macrophage–Monocyte Lineage Cells Is Mediated by Nuclear Factor of Activated T Cells [C] . HIROSHI MINEMATSU, MIKE J. SHIN, AYSE B. CELIL AYDEMIR, Conference on Skeletal Biology and Medicine . 2007

机译：矫形植入物颗粒诱导的肿瘤坏死因子 - 巨噬细胞单核细胞谱系细胞的产生是由活化T细胞的核因子介导的
5. Disruption of Nrf2 Enhances the Upregulation of Nuclear Factor-kappaB Activity Tumor Necrosis Factor-α and Matrix Metalloproteinase-9 after Spinal Cord Injury in Mice [O] . Lei Mao, Handong Wang, Liang Qiao, 2010

机译：Nrf2的破坏增强小鼠脊髓损伤后核因子-kappaB活性肿瘤坏死因子-α和基质金属蛋白酶-9的上调。
6. Phytochemicals ofAristolochia tagalaandCurcuma caesiaexert anticancer effect by tumor necrosis factor-α-mediated decrease in nuclear factor kappaB binding activity [O] . Lakhan Kma, KhetbadeiLysinia Hynniewta Hadem, RajeshwarNath Sharan 2016

机译：植物化学症Tagalaandcurcuma Caesiaexert抗癌患者肿瘤坏死因子-α-介导的核因子κBapb结合活性的降低

Phytochemicals of Aristolochia tagala and Curcuma caesia exert anticancer effect by tumor necrosis factor-α-mediated decrease in nuclear factor kappaB binding activity

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