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Primary Central Nervous System Post-transplant Lymphoproliferative Disorder Diagnosed by Peripheral Facial Nerve Palsy

机译：周围性面神经麻痹诊断原发性中枢神经系统移植后淋巴细胞增生性疾病

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Although primary central nervous system post-transplant lymphoproliferative disorder (PCNS-PTLD) causes various symptoms depending on the tumor region, there has been no previous report of PCNS-PTLD in the cerebellopontine angle that was diagnosed due to peripheral facial nerve palsy. We herein report a case involving a 62-year-old man with PCNS-PTLD in the cerebellopontine angle who was diagnosed due to peripheral facial nerve palsy. The reduction of immunosuppressive therapy, whole-brain radiotherapy, intrathecal chemotherapy, and rituximab were effective in treating this patient. Physicians should therefore be mindful that PCNS-PTLD can cause peripheral facial nerve palsy in renal transplant recipients.

机译：尽管原发性中枢神经系统移植后淋巴细胞增生性疾病（PCNS-PTLD）会根据肿瘤部位而引起各种症状，但先前没有关于小脑桥脑角PCNS-PTLD的报道，该报道是由于周围面神经麻痹而诊断出来的。我们在此报告了一个病例，该病例涉及一名62岁小脑桥角PCNS-PTLD的男子，该男子被诊断为周围性面神经麻痹。减少免疫抑制疗法，全脑放疗，鞘内化疗和利妥昔单抗可有效治疗该患者。因此，医师应注意PCNS-PTLD可导致肾移植受者周围性面神经麻痹。

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期刊名称 Internal Medicine
作者
Aya Imafuku; Kiho Tanaka; Yuji Marui; Yoshifumi Ubara; Kenmei Takaichi; Shinji Tomikawa; Yasunori Ota; Takeshi Fujii; Yasuo Ishii;
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作者单位

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年(卷),期 2018(57),13
年度 2018
页码 1899–1903
总页数 5
原文格式 PDF
正文语种
中图分类基础医学;
关键词
primary central nervous system post-transplant lymphoproliferative disorder peripheral facial nerve palsy cerebellopontine angle tumor;

机译：原发性中枢神经系统移植后淋巴增生性疾病;周围性面神经麻痹;桥小脑角肿瘤;

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专利

1. Primary Central Nervous System Post-transplant Lymphoproliferative Disorder Diagnosed by Peripheral Facial Nerve Palsy [J] . Aya Imafuku, Kiho Tanaka, Yuji Marui, Internal medicine. . 2018,第13期

机译：周围性面神经麻痹诊断原发性中枢神经系统移植后淋巴细胞增生性疾病
2. Susceptibility-weighted imaging and diffusion-weighted imaging findings in central nervous system monomorphic B cell post-transplant lymphoproliferative disorder before and after treatment and comparison with primary B cell central nervous system lymphoma [J] . Ginat Daniel Thomas, Purakal Alixandra, Pytel Peter Journal of neuro-oncology. . 2015,第2期

机译：中枢神经系统单形B细胞移植后淋巴增生性疾病治疗前后的敏感性加权成像和扩散加权成像发现以及与原发性B细胞中枢神经系统淋巴瘤的比较
3. Primary post-transplant lymphoproliferative disorder of the central nervous system: characteristics, management and outcome in 25 paediatric patients [J] . Taj Mary M., Maecker-Kolhoff Britta, Ling Rebecca, British Journal of Haematology . 2021,第6期

机译：中枢神经系统的主要移植后淋巴抑制性疾病：25例儿科患者的特征，管理和结果
4. Treatment of Recurrent Post-transplant LymphoproIIferative Disorder (PTLD) of the Central Nervous System (CNS) with High-dose Methotrexate (HD-MTX) [C] . Twist C.J., Kjelson L., McKenney A., International Small Bowel Transplant Symposium . 2009

机译：用高剂量甲氨蝶呤（HD-MTX）的中枢神经系统（CNS）复发性移植后移植淋巴结疾病（PTLD）的处理
5. The role of the p75 low-affinity neurotrophin receptor in the peripheral and central nervous systems following nerve injury. [D] . Ferri, Catharine Celina. 1998

机译：p75低亲和力神经营养蛋白受体在神经损伤后在周围和中枢神经系统中的作用。
6. LL-02TEMOZOLOMIDE IN PRIMARY CENTRAL NERVOUS SYSTEM POST-TRANSPLANT LYMPHOPROLIFERATIVE DISORDER (CNS-PTLD): A CASE SERIES [O] . Jairam Krishnamurthy, Timothy Greiner, Vijaya Bhatt, 2014

机译：原发性中枢神经系统移植后淋巴增殖性疾病（CNS-PTLD）中的LL-02替莫唑胺：一个病例系列
7. Epstein-Barr virus-positive post-transplant lymphoproliferative disorder of the central nervous system, after renal transplantation with a discrepancy in viral load between peripheral blood and cerebrospinal fluid [O] . Boersma, Marijke Nynke, van der Zanden, Adri, Laverman, Gozewijn Dirk, 2012

机译：肾移植后中枢神经系统的爱泼斯坦-巴尔病毒阳性移植后淋巴组织增生性疾病，外周血和脑脊液之间的病毒载量存在差异

Primary Central Nervous System Post-transplant Lymphoproliferative Disorder Diagnosed by Peripheral Facial Nerve Palsy

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