• 主题
高级搜索  >
历史搜索 清空历史
首页> 美国卫生研究院文献>International Journal of Nephrology >The Relationship between Carotid Atherosclerosis Inflammatory Cytokines and Oxidative Stress in Middle-Aged and Elderly Hemodialysis Patients
【2h】

The Relationship between Carotid Atherosclerosis Inflammatory Cytokines and Oxidative Stress in Middle-Aged and Elderly Hemodialysis Patients

机译：中老年人血液透析患者颈动脉粥样硬化炎性细胞因子与氧化应激的关系

代理获取
本网站仅为用户提供外文OA文献查询和代理获取服务，本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文，但由于OA文献来源多样且变更频繁，仍可能出现获取不到、文献不完整或与标题不符等情况，如果获取不到我们将提供退款服务。请知悉。
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Objective. To identify the relationship between microinflammation, oxidative stress, and carotid arterial stiffness in hemodialysis patients. Methods. The CAS β and PWV obtained by ultrasound technology were used to assess carotid arterial stiffness. We divided the patients into either the CAS group or the non-CAS group based on the presence or absence of CAS. The parameters of ALB, Ca, P, TC, HDL, LDL, TG, glucose, creatinine, and hs-CRP levels were routinely tested in both groups of patients. The levels of TNF-α, IL-6, and 8-isoprostane F2α were measured by ELISA. Results. A total of 42 patients were enrolled in the CAS group and 20 patients were enrolled in the non-CAS group. No significant differences between the CAS group and the non-CAS group were observed with respect to age, dialysis duration, DBP, BUN, Cr, TC, TG, HDL, LDL, and Hb. However, SBP , pulse pressure, and 8-isoprostane levels of the CAS group were higher than those of the non-CAS group. The hs-CRP, TNF-α, and IL-6 levels were elevated in both groups but showed no significant differences. Conclusions. Maintenance of hemodialysis patients exhibits a microinflammatory state that may lead to atherosclerosis. The roles of hypertension and oxidative stress may be more important.
机译：目的。以确定血液透析患者微炎症，氧化应激和颈动脉僵硬度之间的关系。方法。通过超声技术获得的CASβ和PWV用于评估颈动脉僵硬度。我们根据是否存在CAS将患者分为CAS组或非CAS组。两组患者均常规测试了ALB，Ca，P，TC，HDL，LDL，TG，葡萄糖，肌酐和hs-CRP水平的参数。通过ELISA测量TNF-α，IL-6和8-异前列腺素F2α的水平。结果。 CAS组共有42例患者入组，非CAS组共有20例患者入组。在年龄，透析时间，DBP，BUN，Cr，TC，TG，HDL，LDL和Hb方面，CAS组与非CAS组之间无显着差异。然而，CAS组的SBP，脉压和8-异前列腺素水平高于非CAS组。两组的hs-CRP，TNF-α和IL-6水平均升高，但无显着差异。结论。维持血液透析患者表现出微炎症状态，可能导致动脉粥样硬化。高血压和氧化应激的作用可能更为重要。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
代理获取

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号