Ammonium glycyrrhizinate-loaded niosomes as a potential nanotherapeutic system for anti-inflammatory activity in murine models

机译：甘草酸铵负载的脂质体在小鼠模型中作为潜在的抗炎活性纳米治疗系统

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BackgroundLiquorice extracts demonstrate therapeutic efficacy in treating dermatitis, eczema, and psoriasis when compared with corticosteroids. In this work, nonionic surfactant vesicles (niosomes, NSVs) containing polysorbate 20 (Tween 20), cholesterol, and cholesteryl hemisuccinate at different molar concentrations were used to prepare monoammonium glycyrrhizinate (AG)-loaded NSVs. The anti-inflammatory properties of AG-loaded NSVs were investigated in murine models.

机译：背景与甘醇类固醇相比，甘草提取物具有治疗皮炎，湿疹和牛皮癣的疗效。在这项工作中，使用含有不同摩尔浓度的聚山梨酯20（吐温20），胆固醇和半琥珀酸胆甾醇酯的非离子表面活性剂囊泡（脂质体，NSV）制备负载甘草次酸单铵（AG）的NSV。在小鼠模型中研究了载有AG的NSV的抗炎特性。

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期刊名称 International Journal of Nanomedicine
作者
Carlotta Marianecci; Federica Rinaldi; Luisa Di Marzio; Marica Mastriota; Stefano Pieretti; Christian Celia; Donatella Paolino; Michelangelo Iannone; Massimo Fresta; Maria Carafa;
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作者单位

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年(卷),期 2014(9),-1
年度 2014
页码 635–651
总页数 17
原文格式 PDF
正文语种
中图分类生化遗传学;生化药理学;
关键词
niosomes ammonium glycyrrhizinate pH sensitivity cytotoxicity inflammation;

机译：脂质体;甘草酸铵;pH敏感性;细胞毒性;炎症;

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专利

1. Ammonium glycyrrhizinate-loaded niosomes as a potential nanotherapeutic system for anti-inflammatory activity in murine models [J] . Carlotta Marianecci, Federica Rinaldi, Luisa Di Marzio, International Journal of Nanomedicine . 2014,第1期

机译：甘草酸铵负载的脂质体在小鼠模型中作为潜在的抗炎活性纳米治疗系统
2. Anti-inflammatory activity of novel ammonium glycyrrhizinateiosomes delivery system: Human and murine models [J] . Marianecci C., Rinaldi F., Mastriota M., Journal of Controlled Release: Official Journal of the Controlled Release Society . 2012,第1期

机译：新型甘草酸铵/脂质体递送系统的抗炎活性：人和鼠模型
3. PERFORMANCE OF CURCUMIN IN NANOSIZED CARRIERS NIOSOMES AND ETHOSOMES AS POTENTIAL ANTI-INFLAMMATORY DELIVERY SYSTEM FOR TOPICAL APPLICATION [J] . Mona M. El-Mahdy Bulletin of pharmaceutical sciences . 2020,第1期

机译：姜黄素在纳米载体定位性的性能和归属组中的性能作为局部应用的潜在抗炎递送系统
4. Effect of Ammonium Formate and Mixtures of Urea and Ammonium Formate on Low Temperature Activity of SCR Systems [C] . Anu Solla, Marten Westerholm, Christer Soderstrom, SAE World Congress . 2006

机译：甲酸铵和尿素混合物甲酸甲酸混合物对SCR系统低温活性的影响
5. Development and Characterization of Selective CB2R Inverse Agonists as a Novel Anti-inflammatory Therapy for Neuroinflammation: Mechanisms of Action in Murine and Human Microglia Models Provide Valuable Insights into Their Therapeutic Potential [D] . Alghamdi, Sahar Saleh. 2020

机译：选择性CB2R逆激动剂作为一种新型抗炎疗法的开发和特征，成为神经肾性炎症的抗炎治疗：小鼠和人微胶质模型的作用机制为其治疗潜力提供了有价值的见解
6. Anti-inflammatory activity of niosomes entrapped with Plai oil (Zingiber cassumunar Roxb.) by therapeutic ultrasound in a rat model [O] . Jirakrit Leelarungrayub, Jiradej Manorsoi, Aranya Manorsoi 2017

机译：在大鼠模型中通过治疗性超声对夹有Plai油（Zingiber cassumunar Roxb。）的脂质体的抗炎活性
7. Ammonium glycyrrhizinate-loaded niosomes as a potential nanotherapeutic system for anti-inflammatory activity in murine models [O] . Carlotta Marianecci, Federica Rinaldi, Luisa Di Marzio, 2014

机译：甘草酸铵负载的脂质体在小鼠模型中作为潜在的抗炎活性纳米治疗系统

Ammonium glycyrrhizinate-loaded niosomes as a potential nanotherapeutic system for anti-inflammatory activity in murine models

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