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Novel redispersible nanosuspensions stabilized by co-processed nanocrystalline cellulose–sodium carboxymethyl starch for enhancing dissolution and oral bioavailability of baicalin

机译：纳米纤维素-羧甲基淀粉钠共加工稳定的新型可再分散纳米悬浮液可增强黄ical苷的溶解度和口服生物利用度

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摘要

BackgroundTo improve the dissolution and bioavailability of poorly soluble drugs, novel nanosuspensions using co-processed nanocrystalline cellulose–sodium carboxymethyl starch (NCCS) as a synergetic stabilizer were first designed.

机译：背景为了提高难溶性药物的溶解度和生物利用度，首先设计了使用纳米纤维素-羧甲基淀粉钠（NCCS）作为协同稳定剂的共处理纳米悬浮液。

著录项

期刊名称 International Journal of Nanomedicine
作者
Jin Xie; Yijing Luo; Yang Liu; Yueqin Ma; Pengfei Yue; Ming Yang;
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作者单位

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年(卷),期 2019(14),-1
年度 2019
页码 353–369
总页数 17
原文格式 PDF
正文语种
中图分类生化遗传学;生化药理学;
关键词
nanocrystalline cellulose Pickering nanosuspensions nanocrystals solid particles stabilizer oral bioavailability;

机译：纳米晶纤维素;Pickering纳米悬浮液;纳米晶;固体颗粒稳定剂;口服生物利用度;

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专利

1. Dissolution and oral absorption of pranlukast nanosuspensions stabilized by hydroxypropylmethyl cellulose [J] . In-hwan Baek, Jung-Soo Kim, Eun-Sol Ha, International Journal of Biological Macromolecules: Structure, Function and Interactions . 2014,第Null期

机译：羟丙基甲基纤维素稳定的普鲁司特纳米混悬液的溶解和口服吸收
2. Dissolution and oral absorption of pranlukast nanosuspensions stabilized by hydroxypropylmethyl cellulose [J] . In-hwan Baek, Jung-Soo Kim, Eun-Sol Ha, International Journal of Biological Macromolecules: Structure, Function and Interactions . 2014,第Null期

机译：羟丙基甲基纤维素稳定的普鲁司特纳米混悬液的溶解和口服吸收
3. Formulating food protein-stabilized indomethacin nanosuspensions into pellets by fluid-bed coating technology: physical characterization, redispersibility, and dissolution [J] . Wei He, Yi Lu, Jianping Qi, International Journal of Nanomedicine . 2013,第1期

机译：通过流化床包衣技术将食品蛋白质稳定的吲哚美辛纳米混悬剂制成颗粒：物理特性，可再分散性和溶解性
4. Roles of Cellulosic Polymers and Surfactants in the Stabilization of Drug Nanosuspensions and Redispersibility of Dried Composites [C] . Meng Li, Ecevit Bilgili AIChE Meeting . 2015

机译：纤维素聚合物和表面活性剂在药物纳米杆菌稳定中的作用和干复合材料的再分解性
5. Formulating food protein-stabilized indomethacin nanosuspensions into pellets by fluid-bed coating technology: physical characterization redispersibility and dissolution [O] . Wei He, Yi Lu, Jianping Qi, 2013

机译：通过流化床包衣技术将食品蛋白质稳定的消炎痛纳米混悬剂制成颗粒：物理特性可再分散性和溶出度
6. Nanosuspensions Containing Oridonin/HP-β-Cyclodextrin Inclusion Complexes for Oral Bioavailability Enhancement via Improved Dissolution and Permeability [O] . Xingwang Zhang, Tianpeng Zhang, Yali Lan, 2015

机译：纳米皂甙含有奥思蛋白/ HP-β-环糊精的包合物，通过改善的溶解和渗透性来增强口服生物利用度

Novel redispersible nanosuspensions stabilized by co-processed nanocrystalline cellulose–sodium carboxymethyl starch for enhancing dissolution and oral bioavailability of baicalin

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