Effects of budesonide on toll-like receptor expression in alveolar macrophages from smokers with and without COPD

机译：布地奈德对有和无COPD吸烟者肺泡巨噬细胞toll样受体表达的影响

代理获取

本网站仅为用户提供外文OA文献查询和代理获取服务，本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文，但由于OA文献来源多样且变更频繁，仍可能出现获取不到、文献不完整或与标题不符等情况，如果获取不到我们将提供退款服务。请知悉。

页面导航

摘要
著录项
相似文献
相关主题

摘要

IntroductionAlveolar macrophages (AMs) are equipped with innate immune receptors such as toll-like receptor 2 (TLR2) and toll-like receptor 4 (TLR4). In primary bronchial epithelial cells, exposure of toll-like receptor (TLR) ligands or tumor necrosis factor-alpha (TNF-α) increased TLR2 mRNA expression and reduced interleukin-8 (IL-8) release when coincubated with glucocorticosteroids. The aim of this study was to compare TLR2 and TLR4 expression levels and the effect of a glucocorticosteroid after stimulation with TLR ligands on AMs from smokers with and without COPD compared with the healthy controls.

机译：简介肺泡巨噬细胞（AM）配备有先天性免疫受体，例如toll样受体2（TLR2）和toll样受体4（TLR4）。在原代支气管上皮细胞中，与糖皮质激素共孵育时，通行费样受体（TLR）配体或肿瘤坏死因子-α（TNF-α）的暴露可增加TLR2 mRNA表达并减少白介素8（IL-8）释放。这项研究的目的是比较TLR2和TLR4的表达水平，以及与健康对照组相比，用TLR配体刺激后吸烟者在患有COPD和未患有COPD的吸烟者AMs上的作用。

著录项

期刊名称 International Journal of Chronic Obstructive Pulmonary Disease
作者
Jie Ji; Ida von Schéele; Bo Billing; Barbro Dahlén; Ann-Sofie Lantz; Kjell Larsson; Lena Palmberg;
展开▼
作者单位

展开▼
年(卷),期 2016(11),-1
年度 2016
页码 1035–1043
总页数 9
原文格式 PDF
正文语种
中图分类呼吸生理学;
关键词
smokers lipopolysaccarid peptidoglycan glucocorticosteroid;

机译：吸烟者;脂多糖;肽聚糖;糖皮质激素;

相似文献

外文文献
中文文献
专利

1. Effects of budesonide on toll-like receptor expression in alveolar macrophages from smokers with and without COPD [J] . Jie Ji, Ida von Schéele, Bo Billing, International Journal of Chronic Obstructive Pulmonary Disease . 2016,第1期

机译：布地奈德对有无COPD吸烟者肺泡巨噬细胞toll样受体表达的影响
2. Toll-like receptor 2 expression is decreased on alveolar macrophages in cigarette smokers and COPD patients [J] . Daniel Droemann, Torsten Goldmann, Thorsten Tiedje, Respiratory Research . 2005,第1期

机译：吸烟者和COPD患者肺泡巨噬细胞Toll样受体2表达降低
3. The effects of repeated Toll-like receptors 2 and 4 stimulation in COPD alveolar macrophages [J] . Simon R Lea, Sophie L Reynolds, Manminder Kaur, International Journal of Chronic Obstructive Pulmonary Disease . 2018,第1期

机译：重复的Toll样受体2和4刺激对COPD肺泡巨噬细胞的影响
4. Effects of Toll-like Receptor 2 and Toll-like Receptor 4 in Toxoplasma Gondii-Derived Heat Shock Protein 70-induced Tolerance in Nitric Oxide Production [C] . H.S. Mun, F. Aosai, K. Norose, International Congress of Parasitology . 2006

机译：Toll样受体2和Toll样受体4在弓形虫衍生热休克蛋白70诱导耐受氧化氮生产中的影响
5. Contrasting Effects of Triggering Toll-Like Receptors 2, 3, 4, and 7 in the Macrophage Susceptibility to Murine Coronavirus Infections [D] . Mazaleuskaya, Liudmila 2012

机译：触发收费类似受体2，3，4和7在巨噬细胞对小鼠冠状病毒感染的易感性的对比作用。
6. Toll-like receptor 2 expression is decreased on alveolar macrophages in cigarette smokers and COPD patients [O] . Daniel Droemann, Torsten Goldmann, Thorsten Tiedje, 2005

机译：吸烟者和COPD患者肺泡巨噬细胞Toll样受体2表达降低
7. Toll-like receptor 2 expression is decreased on alveolar macrophages in cigarette smokers and COPD patients [O] . 2005

机译：吸烟者和COPD患者肺泡巨噬细胞Toll样受体2表达降低
8. GM-CSF stimulated proliferation of rat alveolar macrophages and the effects of differing particulate burden levels in alveolar macrophages on the proliferative response. [R] . Pendergrass, D., Valdez, Y. E., Lehnert, B. E. 1993

机译：Gm-CsF刺激大鼠肺泡巨噬细胞的增殖和肺泡巨噬细胞中不同颗粒负荷水平对增殖反应的影响。

Effects of budesonide on toll-like receptor expression in alveolar macrophages from smokers with and without COPD

摘要

著录项

相似文献

相关主题

期刊订阅