Non ictal onset zone: A window to ictal dynamics

机译：非冰毒发作区：冰毒动力学的窗口

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The focal and network concepts of epilepsy present different aspects of electroclinical phenomenon of seizures. Here, we present a 23-year-old man undergoing surgical evaluation with left fronto-temporal electrocorticography (ECoG) and microelectrode-array (MEA) in the middle temporal gyrus (MTG). We compare action-potential (AP) and local field potentials (LFP) recorded from MEA with ECoG. Seizure onset in the mesial-temporal lobe was characterized by changes in the pattern of AP-firing without clear changes in LFP or ECoG in MTG. This suggests simultaneous analysis of neuronal activity in differing spatial scales and frequency ranges provide complementary insights into how focal and network neurophysiological activity contribute to ictal activity.

机译：癫痫的焦点和网络概念代表癫痫发作的电子临床现象的不同方面。在这里，我们介绍了一名23岁的男子，他接受了颞中回（MTG）的左额颞颞皮层电描记术（ECoG）和微电极阵列（MEA）进行手术评估。我们比较了用ECoG从MEA记录的动作电位（AP）和局部场电位（LFP）。中颞叶癫痫发作的特征是AP发射模式的改变，而MTG中LFP或ECoG没有明显改变。这表明在不同的空间尺度和频率范围内同时分析神经元活动可提供有关局灶性和网络神经生理活动如何促进发作的补充见解。

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期刊名称 Epilepsy Behavior Case Reports
作者
Pegah Afra; Sara J. Hanrahan; Spencer Sterling Kellis; Paul House;
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作者单位

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年(卷),期 2017(8),-1
年度 2017
页码 123–127
总页数 5
原文格式 PDF
正文语种
中图分类医学行为学;
关键词
Microelectrode array Ictal dynamics Microgrid Single neuron recording Ictal onset;

机译：微电极阵列;局部动力学;微电网;单神经元记录;局部发作;

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专利

1. Non ictal onset zone: A window to ictal dynamics [J] . Pegah Afra, Sara J. Hanrahan, Spencer Sterling Kellis, Epilepsy & Behavior Case Reports . 2017,第2期

机译：非冰毒发作区：冰毒动力学的窗口
2. Ictal onset zone and seizure propagation delineated on ictal F-18 fluorodeoxyglucose positron emission tomography/computed tomography [J] . Madhavi Tripathi, Manjari Tripathi, Ajay Garg, Indian Journal of Nuclear Medicine . 2016,第1期

机译：在F-18氟脱氧葡萄糖正电子发射断层显像/计算机断层显像中描绘了发作期发作区和癫痫发作
3. Ictal SPECT Using an Attachable Automated Injector: Clinical Usefulness in the Prediction of Ictal Onset Zone [J] . JUNG JU LEE, SANG KUN LEE, JANG WUK CHOI Acta Radiologica . 2009,第10期

机译：使用可连接的自动注射器进行Ictal SPECT：预测Ictal发病区的临床实用性
4. Localization of ictal onset zones in Lennox-Gastaut syndrome using directed transfer function method [C] . Cho Jae-Hyun, Jung Young-Jin, Kang Hoon-Chul, 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society . 2011

机译：使用定向传递函数法定位Lennox-Gastaut综合征的发作期区域
5. The pre-ictal manifestations of oxygen neurotoxicity: Correlations between clinical signs and onset of seizures in a swine model of hyperbaric hyperoxia. [D] . Watanabe, Tomas A. A. 2005

机译：氧神经毒性的发作前表现：高压氧血症猪模型的临床体征与癫痫发作的相关性。
6. Goldilocks Zone of Ictal Onset: Partially Recovered Synapses Provide the Kindling to Fuel Ictal Activity [O] . Deepak Subramanian, Viji Santhakumar 2019

机译：发作期的金发姑娘区：部分恢复的突触提供了激发发作的动力。
7. Non ictal onset zone: A window to ictal dynamics [O] . Pegah Afra, Sara J. Hanrahan, Spencer Sterling Kellis, 2017

机译：非发作性发作区：发作期发作的窗口

Non ictal onset zone: A window to ictal dynamics

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