• 主题
高级搜索  >
历史搜索 清空历史
首页> 美国卫生研究院文献>Experimental Diabetes Research >Access to Hemoglobin A1c in Rural Africa: A Difficult Reality with Severe Consequences
【2h】

Access to Hemoglobin A1c in Rural Africa: A Difficult Reality with Severe Consequences

机译：在非洲农村地区获得血红蛋白A1c的情况：后果艰巨后果严重

代理获取
本网站仅为用户提供外文OA文献查询和代理获取服务，本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文，但由于OA文献来源多样且变更频繁，仍可能出现获取不到、文献不完整或与标题不符等情况，如果获取不到我们将提供退款服务。请知悉。
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Sub-Saharan Africa (SSA) continues to have the highest diabetes-related mortality rate in the world. While there exists a multitude of health system barriers driving poor diabetes control, rural facilities particularly in SSA lack access to proper monitoring of glucose and other key biologic tests. At best, most of these diabetes patients receive random blood sugar readings only on the day of their clinic visit. This approach has very limited clinical value in determining dosage adjustments for narrow therapeutic index medications such as insulin. Furthermore, access to other blood tests and physical exam tools for detecting early signs of diabetes complications is limited. We propose that routine access to hemoglobin A1c (HbA1c) testing would not only allow for close monitoring of diabetes control but also provide critical data informing the population level risk for diabetes complications. However, implementing HbA1c testing does have its own barriers at rural facilities, including high costs, refrigeration requirements, and perceived discordance between HbA1c values and mean blood glucose levels for SSA patients. Fortunately, several pilots in rural SSA have illustrated feasibility of HbA1c testing. Further political will, price reduction, and context-specific research are needed. Increasing access to HbA1c testing is a critical step to combat the high diabetes-related mortality rates in rural SSA.
机译：撒哈拉以南非洲（SSA）仍然是世界上与糖尿病相关的最高死亡率。尽管存在许多导致糖尿病控制不佳的卫生系统障碍，但农村地区的设施，特别是撒南非洲地区的乡村设施，无法获得对葡萄糖和其他关键生物学测试的适当监控。充其量，大多数这些糖尿病患者仅在就诊当天才接受随机血糖读数。在确定狭窄治疗指数药物（例如胰岛素）的剂量调整时，这种方法的临床价值非常有限。此外，用于检测糖尿病并发症的早期迹象的其他血液测试和身体检查工具的访问受到限制。我们建议常规访问血红蛋白A1c（HbA1c）测试不仅可以密切监测糖尿病的控制情况，还可以提供重要的数据来告知人群发生糖尿病并发症的风险。但是，在农村设施中实施HbA1c检测确实有其自身的障碍，包括高成本，冷藏要求以及SSA患者的HbA1c值与平均血糖水平之间的不一致性。幸运的是，农村SSA的几名飞行员已经说明了HbA1c测试的可行性。需要进一步的政治意愿，降价和针对具体情况的研究。增加HbA1c检测的可及性是对抗农村SSA中与糖尿病相关的高死亡率的关键步骤。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
代理获取

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号