Neural crest migration: trailblazing ahead

机译：神经c迁移：开拓性发展

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Embryonic cell migration patterns are amazingly complex in the timing and spatial distribution of cells throughout the vertebrate landscape. However, advances in in vivo visualization, cell interrogation, and computational modeling are extracting critical features that underlie the mechanistic nature of these patterns. The focus of this review highlights recent advances in the study of the highly invasive neural crest cells and their migratory patterns during embryonic development. We discuss these advances within three major themes and include a description of computational models that have emerged to more rapidly integrate and test hypothetical mechanisms of neural crest migration. We conclude with technological advances that promise to reveal new insights and help translate results to human neural crest-related birth defects and metastatic cancer.

机译：胚胎细胞的迁移模式在整个脊椎动物景观中的时间和空间分布上极为复杂。但是，体内可视化，细胞询问和计算模型的进步正在提取出关键特征，这些特征是这些模式的机械性质的基础。这篇综述的重点突出了在胚胎发育过程中高侵袭性神经c细胞及其迁移模式研究的最新进展。我们在三个主要主题中讨论了这些进展，并包括对计算模型的描述，这些计算模型可以更快地集成和测试神经integrate迁移的假设机制。我们以技术进步作为结尾，这些技术承诺有望揭示新的见解，并有助于将结果转化为与人类神经rest相关的先天缺陷和转移性癌症。

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期刊名称 F1000 Biology Reports
作者
Paul M. Kulesa; Rebecca McLennan;
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年(卷),期 2015(7),-1
年度 2015
页码 02
总页数 7
原文格式 PDF
正文语种
中图分类生物学;
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专利

1. Neural crest migration: trailblazing ahead [J] . Paul M. Kulesa, Rebecca McLennan F1000 Prime Reports . 2015,第2003期

机译：神经c迁移：开拓创新
2. Vestigial-like 3 is a novel Ets1 interacting partner and regulates trigeminal nerve formation and cranial neural crest migration Vestigial-like 3 is a novel Ets1 interacting partner and regulates trigeminal nerve formation and cranial neural crest migration Vestigial-like 3 is a novel Ets1 interacting partner and regulates trigeminal nerve formation and cranial neural crest migration [J] . Nadine Thézé, Pierre Thiébaud, Corinne Faucheux, Biology Open . 2017,第10期

机译：Vestigial-like 3是一种新型的Ets1相互作用伴侣，并调节三叉神经的形成和颅神经migration迁移Vestigial-like 3是一种新型的Ets1相互作用伴侣，并调节三叉神经的形成和颅神经migration的迁移Vestigial-like 3是一种新型的Ets1相互作用的伴侣并调节三叉神经的形成和颅神经c的迁移
3. The delayed entry of thoracic neural crest cells into the dorsolateral path is a consequence of the late emigration of melanogenic neural crest cells from the neural tube [J] . Reedy MV., Erickson CA., Faraco CD. Developmental biology . 1998,第2期

机译：胸神经neural细胞延迟进入背外侧路径是黑色素生成的神经rest细胞从神经管中晚期移出的结果。
4. Noise-Induced Collective Migration for Neural Crest Cells [C] . Masataka Yamao, Honda Naoki, Shin Ishii ICANN 2010;International conference on artificial neural networks . 2010

机译：噪声诱导的神经rest细胞集体迁移。
5. Study of neural tube closure using forward genetic screens in mice: Novel insight into Rb and cell cycle regulation, and enteric neural crest migration by PP1 and actin interacting protein. [D] . Kim, Tae-Hee. 2006

机译：在小鼠中使用正向遗传筛选对神经管闭合的研究：对Rb和细胞周期调控的新见解，以及PP1和肌动蛋白相互作用蛋白对肠道神经c的迁移。
6. Migration and differentiation of neural crest and ventral neural tube cells in vitro: implications for in vitro and in vivo studies of the neural crest [O] . JF Loring, DL Barker, CA Erickson 1988

机译：神经c和腹侧神经管细胞的体外迁移和分化：对神经rest的体外和体内研究的意义
7. Neural crest migration: trailblazing ahead [O] . Paul M. Kulesa, Rebecca McLennan 2015

机译：神经嵴迁移：未来开拓

Neural crest migration: trailblazing ahead

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