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首页> 美国卫生研究院文献>International Journal of Clinical and Experimental Pathology >Primary extradural meningiomas in head: a report of 19 cases and review of literature
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Primary extradural meningiomas in head: a report of 19 cases and review of literature

机译：头部硬膜外原发性脑膜瘤：19例报告并文献复习

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Primary extradural meningiomas (PEMs) in head were rare tumors. Here we analyzed 231 cases of PEMs in head (including our 19 cases) reported in the literature during the CT era. We found that PEMs in head accounted for 0.8%-1.8% of all meningiomas. The constituent ratio of male PEMs in head increases markedly. PEMs in head have bimodal distribution of ages. The most common presenting symptom was a mass in the region of the lesion. The average duration of symptom was 2.38 years. The skull convexities, paranasal sinuse and nasal cavity, and middle ear ranked as the top three of all sites of tumors. The most common type was Type II (calvarial or diploic). Among 231 cases, total, subtotal and partial removals of tumors were achieved in 89%, 5.5% and 3.1% respectively, and no death occurred perioperatively in all patients. 90% were benign, 5.6% atypical and 3.9% malignant in the 231 cases. The most common histopathological subtype was meningothelial meningioma. The recurrence and tumor-related death rates were 22.4% and 8.2% respectively during a mean 3.03-year follow-up. Our results demonstrate that PEMs in head have some marked clinical characteristics compared with primary intradural meningiomas. Total tumor removal together with a wide excision of all involved tissues followed by the reconstruction of tissue defects is the best surgical project. The prognoses are good in the benign cases after complete surgical resections.
机译：头部硬膜外原发性脑膜瘤（PEM）是罕见的肿瘤。在这里，我们分析了CT时代文献中报道的231例PEMs头部（包括19例）。我们发现头部中的PEM占所有脑膜瘤的0.8％-1.8％。头部中男性PEM的组成比例显着增加。头部的PEM具有年龄的双峰分布。最常见的症状是病变区域的肿块。平均症状持续时间为2.38年。颅骨凸，鼻旁鼻窦和鼻腔以及中耳位列所有肿瘤部位的前三位。最常见的类型是II型（颅骨或双侧）。在231例患者中，肿瘤的全部，次全切除和部分切除分别达到了89％，5.5％和3.1％，并且所有患者的围手术期均未发生死亡。在231例病例中，良性90％，非典型性5.6％，恶性3.9％。最常见的组织病理学亚型是脑膜脑膜瘤。在平均3.03年的随访中，复发率和与肿瘤相关的死亡率分别为22.4％和8.2％。我们的结果表明，与原发性硬脑膜内脑膜瘤相比，头部的PEM具有明显的临床特征。最好的手术方案是将肿瘤全部切除，并广泛切除所有受累组织，然后重建组织缺损。手术切除后的良性病例预后良好。

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