• 主题
高级搜索  >
历史搜索 清空历史
首页> 美国卫生研究院文献>PLoS Clinical Trials >Assessing Potentially Inappropriate Prescribing in Community-Dwelling Older Patients Using the Updated Version of STOPP-START Criteria: A Comparison of Profiles and Prevalences with Respect to the Original Version
【2h】

Assessing Potentially Inappropriate Prescribing in Community-Dwelling Older Patients Using the Updated Version of STOPP-START Criteria: A Comparison of Profiles and Prevalences with Respect to the Original Version

机译：使用更新版本的STOPP-START标准评估社区居住的老年患者中可能不适当的处方：相对于原始版本的概况和患病率比较

代理获取
本网站仅为用户提供外文OA文献查询和代理获取服务，本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文，但由于OA文献来源多样且变更频繁，仍可能出现获取不到、文献不完整或与标题不符等情况，如果获取不到我们将提供退款服务。请知悉。
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Emerging and changing evidence made it necessary to update STOPP-START criteria, and version 2 was published recently. In this study the objectives were to determine the prevalence of potentially inappropriate medication prescribing (PIM) in primary care using STOPP versions 1 (v1) and 2 (v2), as well as 2012 AGS Beers criteria, and analyze the factors associated with inappropriate prescribing according to STOPP/START v2. A cross-sectional study was carried out including community-dwelling older adults over the age of 65. Sociodemographic, clinical, functional and comprehensive drug therapy data were collected. The primary endpoint was the percentage of patients receiving at least one PIM. This variable was measured using three tools: STOPP v1, 2012 AGS Beers criteria and STOPP v2. Similarly, the percentage of patients receiving at least one potential prescribing omission (PPO) was calculated using START versions 1 and 2. A total of 1,615 prescriptions were reviewed. The median number of medications per patient was 7.1 drugs (±3.8). The prevalence of elderly people exposed to polypharmacy (≥5 medications) was 72.9%, whereas 28.4% of the participants took ≥10 drugs regularly. PIM were present in 18.7%, 37.3% and 40.4% of participants, according to the STOPP v1, 2012 Beers criteria and STOPP v2, respectively. According to STOPP v2, the number of medications taken (OR: 1.14, 1.06–1.25), the presence of a psychological disorder (OR: 2.22, 1.13–4.37) and insomnia (OR: 3.35, 1.80–6.32) were risk factors for taking a PIM. The prevalence of PPOs was 34.7% and 21.8% according to version 1 and 2, respectively. In conclusion, STOPP-START criteria have been remarkably modified, which is evidenced by the different prevalence rates detected using version 2, as compared to version 1. In fact, the level of agreement between version 1 and the updated version is only moderate. Special attention should be paid on benzodiazepines, which keep being the most frequent PIM.
机译：越来越多的证据表明有必要更新STOPP-START标准，并且最近发布了版本2。在这项研究中，目标是使用STOPP版本1（v1）和2（v2）以及2012 AGS Beers标准确定初级保健中潜在不适当的药物处方（PIM）的患病率，并分析与不适当处方相关的因素根据STOPP / START v2。进行了一项横断面研究，纳入了65岁以上社区居民的老年人。收集了社会人口统计学，临床，功能和全面的药物治疗数据。主要终点是接受至少一种PIM的患者百分比。使用三个工具测量了该变量：STOPP v1、2012 AGS Beers标准和STOPP v2。同样，使用START版本1和START 2计算了至少接受一种可能的处方遗漏（PPO）的患者百分比。共审查了1,615张处方。每位患者的药物中位数为7.1种药物（±3.8）。接触多药（≥5种药物）的老年人患病率为72.9％，而28.4％的参与者定期服用≥10种药物。根据STOPP v1、2012 Beers标准和STOPP v2，分别有18.7％，37.3％和40.4％的参与者参加了PIM。根据STOPP v2，服用药物的数量（OR：1.14，1.06-–1.25），心理障碍的存在（OR：2.22，1.13–4.37）和失眠（OR：3.35，1.80–6.32）是导致糖尿病的危险因素。采取PIM。根据版本1和版本2，PPO的患病率分别为34.7％和21.8％。总之，STOPP-START标准已得到显着修改，这可以通过使用版本2与版本1所检测到的不同患病率来证明。实际上，版本1和更新版本之间的一致程度仅适中。应特别注意苯二氮卓，苯二氮卓一直是最频繁的PIM。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
代理获取

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号