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首页> 美国卫生研究院文献>Wiley-Blackwell Online Open >Smartphone‐based clinical diagnostics: towards democratization of evidence‐based health care
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Smartphone‐based clinical diagnostics: towards democratization of evidence‐based health care

机译：基于智能手机的临床诊断：实现基于证据的医疗保健的民主化

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Recent advancements in bioanalytical techniques have led to the development of novel and robust diagnostic approaches that hold promise for providing optimal patient treatment, guiding prevention programs and widening the scope of personalized medicine. However, these advanced diagnostic techniques are still complex, expensive and limited to centralized healthcare facilities or research laboratories. This significantly hinders the use of evidence‐based diagnostics for resource‐limited settings and the primary care, thus creating a gap between healthcare providers and patients, leaving these populations without access to precision and quality medicine. Smartphone‐based imaging and sensing platforms are emerging as promising alternatives for bridging this gap and decentralizing diagnostic tests offering practical features such as portability, cost‐effectiveness and connectivity. Moreover, towards simplifying and automating bioanalytical techniques, biosensors and lab‐on‐a‐chip technologies have become essential to interface and integrate these assays, bringing together the high precision and sensitivity of diagnostic techniques with the connectivity and computational power of smartphones. Here, we provide an overview of the emerging field of clinical smartphone diagnostics and its contributing technologies, as well as their wide range of areas of application, which span from haematology to digital pathology and rapid infectious disease diagnostics.
机译：生物分析技术的最新进展导致了新颖而强大的诊断方法的发展，这些方法有望为患者提供最佳治疗，指导预防计划并扩大个性化医学的范围。但是，这些先进的诊断技术仍然很复杂，昂贵，并且仅限于集中式医疗设施或研究实验室。这极大地阻碍了在资源有限的环境和初级保健中使用基于证据的诊断程序，从而在医疗保健提供者和患者之间造成了鸿沟，使这些人群无法获得精确和优质的药物。基于智能手机的成像和传感平台正成为弥合这一差距并分散诊断测试的有前途的替代方案，这些测试提供了诸如便携性，成本效益和连接性等实用功能。此外，为了简化和自动化生物分析技术，生物传感器和芯片实验室技术已成为连接和整合这些测定的必不可少的部分，将诊断技术的高精度和高灵敏度与智能手机的连接性和计算能力结合在一起。在这里，我们概述了临床智能手机诊断技术及其应用技术的新兴领域，以及它们的广泛应用领域，从血液学到数字病理学以及快速传染病诊断。

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