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首页> 外文期刊>Journal of Internal Medicine >Smartphone-based clinical diagnostics: towards democratization of evidence-based health care
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Smartphone-based clinical diagnostics: towards democratization of evidence-based health care

机译：基于智能手机的临床诊断：走向基于证据的卫生保健民主化

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摘要

Recent advancements in bioanalytical techniques have led to the development of novel and robust diagnostic approaches that hold promise for providing optimal patient treatment, guiding prevention programs and widening the scope of personalized medicine. However, these advanced diagnostic techniques are still complex, expensive and limited to centralized healthcare facilities or research laboratories. This significantly hinders the use of evidence-based diagnostics for resource-limited settings and the primary care, thus creating a gap between healthcare providers and patients, leaving these populations without access to precision and quality medicine. Smartphone-based imaging and sensing platforms are emerging as promising alternatives for bridging this gap and decentralizing diagnostic tests offering practical features such as portability, cost-effectiveness and connectivity. Moreover, towards simplifying and automating bioanalytical techniques, biosensors and lab-on-a-chip technologies have become essential to interface and integrate these assays, bringing together the high precision and sensitivity of diagnostic techniques with the connectivity and computational power of smartphones. Here, we provide an overview of the emerging field of clinical smartphone diagnostics and its contributing technologies, as well as their wide range of areas of application, which span from haematology to digital pathology and rapid infectious disease diagnostics.
机译：生物分析技术的最新进步导致开发新颖且稳健的诊断方法，以实现提供最佳患者治疗，指导预防计划和扩大个性化医学范围的承担。然而，这些先进的诊断技术仍然很复杂，昂贵，并且限于集中的医疗保健设施或研究实验室。这显着阻碍了对资源限制的设置和初级保健的基于证据的诊断，从而产生了医疗保健提供者和患者之间的差距，将这些人群留在没有精确和优质的药物。基于智能手机的成像和传感平台是由于承诺遍历这种差距和分散诊断测试的有前途的替代方案，提供了便携性，成本效益和连通性等实际功能。此外，为了简化和自动化生物分析技术，生物传感器和实验室技术对界面和整合这些测定来说是必不可少的，使智能手机的连接和计算能力汇集了诊断技术的高精度和敏感性。在这里，我们提供了临床智能手机诊断的新兴领域及其贡献技术的概述，以及它们广泛的应用领域，从血液学到数字病理学和快速传染病诊断。

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  • 来源
    《Journal of Internal Medicine》 |2019年第1期|共21页
  • 作者

    Hernandez-Neuta I.; Neumann F.; Brightmeyer J.; Tis T. Ba; Madaboosi N.; Wei Q.; Ozcan A.; Nilsson M.;

  • 作者单位

    Stockholm Univ Dept Biochem &

    Biophys Sci Life Lab SE-17165 Solna Sweden;

    Stockholm Univ Dept Biochem &

    Biophys Sci Life Lab SE-17165 Solna Sweden;

    North Carolina State Univ Dept Chem &

    Biomol Engn Raleigh NC 27695 USA;

    North Carolina State Univ Dept Mat Sci &

    Engn Box 7907 Raleigh NC 27695 USA;

    Stockholm Univ Dept Biochem &

    Biophys Sci Life Lab SE-17165 Solna Sweden;

    North Carolina State Univ Dept Chem &

    Biomol Engn Raleigh NC 27695 USA;

    Univ Calif Los Angeles Elect &

    Comp Engn Dept Los Angeles CA 90095 USA;

    Stockholm Univ Dept Biochem &

    Biophys Sci Life Lab SE-17165 Solna Sweden;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 内科学;
  • 关键词

    Biosensors; Diagnostics; Digital pathology; Lab-on-a-chip; Smartphones;

    机译：生物传感器;诊断;数字病理学;芯片实验室;智能手机;

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