首页> 美国卫生研究院文献>Wiley-Blackwell Online Open >The co‐formulation of insulin degludec and insulin aspart lowers fasting plasma glucose and rates of confirmed and nocturnal hypoglycaemia independent of baseline glycated haemoglobin levels disease duration or body mass index: A pooled meta‐analysis of phase III studies in patients with type 2 diabetes

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The co‐formulation of insulin degludec and insulin aspart lowers fasting plasma glucose and rates of confirmed and nocturnal hypoglycaemia independent of baseline glycated haemoglobin levels disease duration or body mass index: A pooled meta‐analysis of phase III studies in patients with type 2 diabetes

机译：地格曲胰岛素和门冬胰岛素的共同配方可降低空腹血糖确诊和夜间低血糖发生率而与基线糖化血红蛋白水平疾病持续时间或体重指数无关：对2型患者进行的III期研究汇总荟萃分析糖尿病

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AimsTo investigate whether the proven benefits of insulin degludec (IDeg) combined with insulin aspart (IAsp), known as IDegAsp, given twice daily, extend across a wide spectrum of patients with diabetes.

机译：目的研究每日两次给予的地德格胰岛素（IDeg）与门冬胰岛素（IAsp）（称为IDegAsp）组合的已证实的益处是否扩展到广泛的糖尿病患者中。

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期刊名称 Wiley-Blackwell Online Open
作者
Martin Haluzík; Greg Fulcher; Thomas R. Pieber; Lars Bardtrum; Deniz Tutkunkardas; Helena W. Rodbard;
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作者单位

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年(卷),期 -1(20),7
年度 -1
页码 1585–1592
总页数 8
原文格式 PDF
正文语种
中图分类
关键词
glycaemic control hypoglycaemia insulin analogues meta‐analysis randomized trial type 2 diabetes;

机译：血糖控制;低血糖;胰岛素类似物;荟萃分析;随机试验;2型糖尿病;

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1. The co-formulation of insulin degludec and insulin aspart lowers fasting plasma glucose and rates of confirmed and nocturnal hypoglycaemia, independent of baseline glycated haemoglobin levels, disease duration or body mass index: A pooled meta-analysis of phase III studies in patients with type 2 diabetes [J] . Haluzik Martin, Fulcher Greg, Pieber Thomas R., Diabetes, obesity & metabolism . 2018,第7期

机译：胰岛素Degludec和胰岛素Aspart的共同制剂降低了禁食血浆葡萄糖和确诊和夜间低血糖血症的速率，与基线糖化血红蛋白水平，疾病持续时间或体重指数无关：2型患者III期研究的合并的荟萃分析糖尿病
2. Twice-daily insulin degludec/insulin aspart provides superior fasting plasma glucose control and a reduced rate of hypoglycaemia compared with biphasic insulin aspart 30 in insulin-naive adults with Type 2 diabetes [J] . Franek E., Haluzik M., Varzic S. Canecki, Diabetic medicine: A journal of the British Diabetic Association . 2016,第4期

机译：与未使用胰岛素的2型糖尿病成人相比，与双相胰岛素aspart 30相比，每天两次胰岛素degludec / aspart胰岛素可提供更好的空腹血糖控制，降低低血糖发生率
3. Insulin degludec results in lower rates of nocturnal hypoglycaemia and fasting plasma glucose vs. insulin glargine: A meta-analysis of seven clinical trials [J] . Russell-Jones D., Gall M. -A., Niemeyer M., Nutrition, metabolism, and cardiovascular diseases: NMCD . 2015,第10期

机译：与甘精胰岛素相比，地德胰岛素能降低夜间低血糖发生率和空腹血糖：一项七项临床试验的荟萃分析
4. Twice‐daily insulin degludec/insulin aspart provides superior fasting plasma glucose control and a reduced rate of hypoglycaemia compared with biphasic insulin aspart 30 in insulin‐naïve adults with Type 2 diabetes [O] . E. Franek, M. Haluzík, S. Canecki Varžić, -1

机译：与未接受过胰岛素治疗的2型糖尿病成年人中的双相胰岛素aspart 30相比每日两次地格胰岛素/门冬胰岛素可提供更好的空腹血糖控制和降低的低血糖发生率
5. Insulin degludec results in lower rates of nocturnal hypoglycaemia and fasting plasma glucose vs. insulin glargine: A meta-analysis of seven clinical trials [O] . Russell-Jones, D, Gall, M.-A., Niemeyer, M., 2015

机译：与甘精胰岛素相比，地德胰岛素能降低夜间低血糖和空腹血糖的发生率：一项七项临床试验的荟萃分析

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