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首页> 美国卫生研究院文献>Wiley-Blackwell Online Open >A proposal to improve clarity and communication in the EU Classification process for chemicals for carcinogenicity and reproductive and developmental toxicity
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A proposal to improve clarity and communication in the EU Classification process for chemicals for carcinogenicity and reproductive and developmental toxicity

机译：一项提案旨在提高欧盟对致癌性生殖和发育毒性的化学品的分类程序的清晰度和沟通能力

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There is an issue in the EU classification of substances for carcinogenicity and for reproductive or developmental toxicity which has brought difficulties to those involved in the process. The issue lies in the inability of the classification system to distinguish between carcinogens and reproductive toxicants with different levels of concern. This has its origins in the early years of toxicology when it was thought that a relatively small number of chemicals would be either carcinogens or reproductive toxicants, but this has turned out not to be the case. This can cause problems in communicating to the users of chemicals, including the public, the nature of the hazard presented by chemicals. Processes have been developed within the classification system for setting specific concentration limits which assess the degree of hazard for carcinogens and reproductive toxicants as high, medium or low. However these categories are not otherwise used in classification. It is proposed that their wider use would bring the advantages of transparency, clarity of communication, certainty of the process and would allow chemicals with a high degree of hazard to be identified and managed in an appropriate way. Copyright © 2014. The Authors. Journal of Applied Toxicology Published by John Wiley & Sons Ltd.The inability of the EU classification system to distinguish between carcinogens and reproductive toxicants with different levels of concern can cause problems in communicating to the users of chemicals the nature of the hazard presented by chemicals. Processes have been developed by the EU for assessing the degree of hazard for carcinogens and reproductive toxicants as high, medium or low. Using them more widely would bring the advantage of transparency, clarity of communication and certainty of the process.
机译：在欧盟的致癌性和生殖或发育毒性物质分类中存在一个问题，这给参与该过程的人们带来了困难。问题在于分类系统无法区分关注程度不同的致癌物和生殖毒物。这起源于毒理学的早期，当时人们认为相对较少的化学物质是致癌物或生殖毒物，但事实并非如此。这可能会在与化学品使用者（包括公众）进行沟通时，引起化学品所带来危害的性质方面的问题。在分类系统中已经开发出了用于设置特定浓度限值的方法，这些限值可评估致癌物和生殖毒物的危害程度为高，中或低。但是，这些类别未在分类中使用。建议广泛使用它们将带来透明，沟通清晰，过程确定性的优势，并允许以适当方式识别和管理具有高度危害的化学品。版权所有©2014。作者。约翰·威利父子有限公司（John Wiley＆Sons Ltd.）出版的《应用毒理学杂志》（EU）分类体系无法区分关注程度不同的致癌物质和生殖毒性物质，可能会导致向化学品使用者传达化学品所致危害性质的问题。欧盟已经开发了评估致癌物质和生殖毒性物质高，中或低危害程度的方法。更加广泛地使用它们将带来透明，沟通清晰和过程确定性的优势。

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