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首页> 外文期刊>Journal of applied toxicology >A proposal to improve clarity and communication in the EU Classification process for chemicals for carcinogenicity and reproductive and developmental toxicity
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A proposal to improve clarity and communication in the EU Classification process for chemicals for carcinogenicity and reproductive and developmental toxicity

机译:提高核原性和生殖和发育毒性的欧盟化学品中欧盟分类过程中清晰度和沟通的建议

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摘要

There is an issue in the EU classification of substances for carcinogenicity and for reproductive or developmental toxicity which has brought difficulties to those involved in the process. The issue lies in the inability of the classification system to distinguish between carcinogens and reproductive toxicants with different levels of concern. This has its origins in the early years of toxicology when it was thought that a relatively small number of chemicals would be either carcinogens or reproductive toxicants, but this has turned out not to be the case. This can cause problems in communicating to the users of chemicals, including the public, the nature of the hazard presented by chemicals. Processes have been developed within the classification system for setting specific concentration limits which assess the degree of hazard for carcinogens and reproductive toxicants as high, medium or low. However these categories are not otherwise used in classification. It is proposed that their wider use would bring the advantages of transparency, clarity of communication, certainty of the process and would allow chemicals with a high degree of hazard to be identified and managed in an appropriate way. Copyright (C) 2014. The Authors. Journal of Applied Toxicology Published by John Wiley & Sons Ltd.
机译:欧盟物质分类存在致癌性和生殖或发育毒性的问题,这对参与该过程的人带来了困难。该问题在于分类系统的无法区分致癌物质和生殖毒物不同的关注水平。这在毒理学的早期毒理学中有其来源的起源,据认为是一种相对少量的化学物质是致癌物质或生殖毒性的,但这已经证明了不是这种情况。这可能导致与包括公众在内的化学物质的用户沟通的问题,化学品呈递的危险性质。已经在分类系统内开发了用于设定特定浓度限制的过程,这些限制评估致癌性和生殖毒物的危害程度,以及高,中或低。但是,这些类别在分类中没有其他任何类别。建议他们更广泛的使用将带来透明度,沟通清晰度,肯定的过程,并且可以以适当的方式确定和管理具有高度危险的化学品。版权所有(c)2014.作者。 John Wiley&Sons Ltd.出版的应用毒理学杂志CHINESE

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