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Clinicians’ Reasons for Deviations from Recommended Dosing Practices for Antipsychotic Medications

机译:临床医生偏离抗精神病药物推荐给药方法的原因

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Objective This study was designed to investigate clinician rationales for prescribing higher than recommended dosages of antipsychotic medications in patients with schizophrenia. Methods Prescribers for all patients at two VA medical centers whose dosage exceeded PORT recommendations were interviewed. Results For 91/107 (85%) of patients, the prescriber responded that the current dosage should not be decreased. Positive symptoms were the most common target symptoms (94%), followed by negative symptoms (26%), anxiety (23%), and insomnia (13%). Conclusions In patients receiving higher than recommended dosages of antipsychotics, clinicians were frequently able to cite specific target symptoms.
机译:目的本研究旨在探讨为精神分裂症患者开出高于推荐剂量的抗精神病药物的临床理由。方法采访了两个VA医疗中心所有剂量超过PORT建议剂量的患者的处方。结果对于91/107(85%)的患者,处方者回答不应减少当前剂量。阳性症状是最常见的目标症状(94%),其次是阴性症状(26%),焦虑症(23%)和失眠(13%)。结论在接受高于推荐剂量的抗精神病药的患者中,临床医生通常能够列举特定的目标症状。

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