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Ultrathin Organic Electrochemical Transistor with Nonvolatile and Thin Gel Electrolyte for Long-Term Electrophysiological Monitoring

机译:具有非易失性和薄凝胶电解质的超薄有机电化学晶体管,用于长期电生理监测

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摘要

Skin-based electrical-signal monitoring is one of the basic and noninvasive diagnostic methods for observing vital signals that contain valuable information about the dynamic status of the inner body. Soft bioelectronic devices are developed for the acquisition of high-quality biosignals by taking advantage of their inherent thin and soft bodies. Among these devices, the organic electrochemical transistor (OECT) is a promising local transducing amplifier because of its key advantages, such as low operating voltage, high transconductance, and biocompatibility. However, the transistor's direct electrolyte-gated operation limits its ability to measure biosignals only when the electrolyte exists. Here, an ultrathin OECT-based wearable electrophysiological sensor based on a thin (approximate to 6 mu m) and nonvolatile gel electrolyte is reported, which can operate on dry biological surfaces. This sensor can measure biopotentials with a high mechanical stability and high signal-to-noise ratio (24 dB) even from dry surfaces of the human body and also shows stable performance during long-term continuous monitoring and multiple reuse in a test that lasted more than a week.
机译:基于皮肤的电信号监测是观察生命信号的基本和非侵入性诊断方法之一,生命信号包含有关体内动态状态的宝贵信息。开发软生物电子设备是为了利用其固有的薄而柔软的本体来获取高质量的生物信号。在这些设备中,有机电化学晶体管(OECT)由于其诸如低工作电压,高跨导和生物相容性等关键优势而成为有前途的本地换能放大器。然而,晶体管的直接电解质门控操作仅在电解质存在时限制了其测量生物信号的能力。在此,报道了一种基于OECT的超薄可穿戴式电生理传感器,该传感器基于稀薄(约6微米)且不挥发的凝胶电解质,可在干燥的生物表面上工作。该传感器即使在干燥的人体表面上也可以测量具有高机械稳定性和高信噪比(24 dB)的生物电势,并且在长期持续监测和多次重复使用的测试中表现出稳定的性能,持续时间更长超过一个星期。

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