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Modus Operandi of Simultaneous Covering Synthesis from Precursor Heterogeneity for Shelled Nanorods for Multipotent Cancer Theranostics

机译:从前体异质性同时覆盖壳的纳米棒用于多能性癌症治疗学的同时覆盖合成的方法

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摘要

The synthesis of nanostructures using homogeneous precursors in the solution phase is widely used to achieve uniformity and well-defined morphological control. However, drawbacks such as the lack of diversity due to the limited reaction rate modulation exist. One-step, core-shell nanorod formation using simultaneous covering synthesis using solid and ionic heterogeneous precursors is proposed in this study. A Te-Bi2Te3/TeO2 core-shell structure is successfully synthesized by precisely controlling various influencing factors, including concentration, temperature, and pH, and its physicochemical and photochemical properties are thoroughly investigated. The proposed nanostructure overcomes the oxidation susceptibility of Te and can be applied to multipotent cancer theranostics in vitro and in vivo in combination with computed tomography imaging.
机译:在溶液相中使用均相前体合成纳米结构被广泛用于实现均匀性和明确的形态控制。然而,存在诸如由于有限的反应速率调节而导致的缺乏多样性的缺点。在这项研究中,提出了使用固体和离子异质前体同时覆盖合成的一步一步核壳纳米棒形成方法。通过精确控制浓度,温度和pH等多种影响因素,成功合成了Te-Bi2Te3 / TeO2核-壳结构,并对其理化性质和光化学性质进行了深入研究。拟议的纳米结构克服了Te的氧化敏感性,可与计算机断层扫描成像相结合,在体外和体内应用于多能性癌症治疗。

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  • 来源
    《Advanced Functional Materials》 |2020年第9期|1907203.1-1907203.13|共13页
  • 作者单位

    Kwangwoon Univ Dept Chem Seoul 01897 South Korea;

    Kwangwoon Univ Dept Chem Seoul 08826 South Korea;

    Incheon Natl Univ Dept Chem 119 Acad Ro Incheon 22012 South Korea;

    Korea Inst Sci & Technol Inst Adv Composite Mat Carbon Composite Mat Res Ctr San 101 Wanju Gun 565905 Jeollabuk Do South Korea;

    Korea Inst Sci & Technol Inst Adv Composite Mat Carbon Composite Mat Res Ctr San 101 Wanju Gun 565905 Jeollabuk Do South Korea|Dongguk Univ Dept Chem Seoul Campus Seoul 04620 South Korea;

    Kwangwoon Univ Dept Chem Seoul 08826 South Korea|Lemonex Inc Inst Biotherapeut Convergence Technol Seoul 08826 South Korea|Seoul Natl Univ IBS Ctr RNA Res Seoul 08826 South Korea;

  • 收录信息
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    bismuth; cancer therapy; hydrothermal; nanorods; tellurium;

    机译:铋;癌症治疗;水热纳米棒碲;

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