• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Advanced Functional Materials >Recent Advances in Host-Guest Self-Assembled Cyclodextrin Carriers: Implications for Responsive Drug Delivery and Biomedical Engineering
【24h】

Recent Advances in Host-Guest Self-Assembled Cyclodextrin Carriers: Implications for Responsive Drug Delivery and Biomedical Engineering

机译：宿主客人自组装环糊精运营商的最新进展：对响应药物交付和生物医学工程的影响

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

This Review is an overview of the unique characteristics of cyclodextrin in forming an inclusion complex via host-guest noncovalent interactions. The modification of cyclodextrin advances its application as a pharmaceutical solubilizer, fabrication of functional molecular machines such as polyrotaxane, polypseudorotaxane, and polycatenanes and grafting of cyclodextrin with different linear, branched chain polymers. The different stimuli-based supramolecular assemblies involving cyclodextrin as a key mediator with linked triggering responses on payload release is highlighted. In addition, the applications of cyclodextrin in diagnostic imaging and medical devices is briefly demonstrated. Cyclodextrin is a relatively low cost, biocompatible, biodegradable, and highly explored material with low toxicity for drug formulation, drug delivery, and wide varieties of other biomedical applications such as those in medical devices fabrication, biosensor, tissue engineering, and bio-imaging. The toxicological profile of cyclodextrin is well established and safe for human consumption in food and medicine.
机译：审查概述了通过宿主客人非共价相互作用形成包含复合物的环糊精的独特特征概述。环糊精的改性将其应用作为药物增溶剂，诸如多甲烷，息氨酸和聚酰烷烃等功能分子机的制备以及具有不同线性的支链聚合物的环糊精的环糊精的嫁接。突出了涉及环糊精的基于刺激的超分子组件作为有效载荷释放的连接触发响应的关键介体。此外，简要展示了环糊精在诊断成像和医疗装置中的应用。环糊精是一种相对较低的成本，生物相容性，可生物降解和高探索的材料，具有低毒性的药物制剂，药物递送和其他生物医学应用的宽品种，例如医疗器械制造，生物传感器，组织工程和生物成像。环糊精的毒理学谱确立，对食品和药物的人类消费很好。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号