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Natural Wax for Transient Electronics

机译：瞬态电子用天然蜡

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摘要

Emerging classes of bioresorbable electronic materials serve as the basis for active biomedical implants that are capable of providing sensing, monitoring, stimulating, and other forms of function over an operating period matched to biological processes such as wound healing. These platforms are of interest because subsequent dissolution, enzymatic degradation, and/or bioresorption can eliminate the need for surgical extraction. This report introduces natural wax materials as long-lived, hydrophobic encapsulation layers for such systems, where biodegradation eventually occurs by chain scission. Studies of wax stability as an encapsulation material demonstrate the ability to retain operation of underlying biodegradable electronic systems for durations between a few days to a few weeks during complete immersion in aqueous solutions in ex-vivo physiological conditions. Electrically conductive composites result from the addition of tungsten microanoparticles, as a conductive, printable paste with similar lifetimes. Demonstrations of these materials in partially biodegradable wireless light-emitting diodes and near-field communication circuits illustrate their use in functional bioresorbable electronic systems. Investigations in animal models reveal no signs of toxicity or other adverse biological responses.%1801819.1-1801819.10
机译：新兴类别的可生物吸收电子材料用作活性生物医学植入物的基础，该植入物能够在与生物学过程（例如伤口愈合）相匹配的工作时间内提供感测，监视，刺激和其他形式的功能。这些平台之所以令人感兴趣，是因为随后的溶解，酶促降解和/或生物吸收可以消除外科手术提取的需要。该报告介绍了天然蜡材料作为此类系统的长寿命疏水包封层，最终通过断链发生生物降解。蜡稳定性作为封装材料的研究表明，在离体生理条件下完全浸入水溶液中的过程中，可以将基础的可生物降解电子系统的运行保持几天到几周的能力。导电复合材料是由钨微粒/纳米颗粒的添加而产生的，作为具有相似寿命的可印刷导电浆料。这些材料在部分可生物降解的无线发光二极管和近场通信电路中的演示说明了它们在功能性可生物吸收电子系统中的用途。动物模型研究显示没有毒性或其他不良生物学反应的迹象。％1801819.1-1801819.10

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  • 来源
    《Advanced Functional Materials》 |2018年第32期|1801819.1-1801819.10|共10页
  • 作者

    Won Sang Min; Koo Jahyun; Crawford Kaitlyn E.; Mickle Aaron D.; Xue Yeguang; Min Seunghwan; McIlvried Lisa A.; Yan Ying; Kim Sung Bong; Lee Seung Min; Kim Bong Hoon; Jang Hokyung; MacEwan Matthew R.; Huang Yonggang; Gereau Robert W.; Rogers John A.;

  • 作者单位

    Univ Illinois, Frederick Seitz Mat Res Lab, Dept Elect & Comp Engn, Urbana, IL 61801 USA;

    Northwestern Univ, Dept Mat Sci & Engn, Evanston, IL 60208 USA;

    Univ Cent Florida, Dept Mat Sci & Engn, Orlando, FL 32816 USA;

    Washington Univ, Sch Med, Dept Anesthesiol, Pain Ctr, St Louis, MO 63130 USA;

    Northwestern Univ, Dept Mech Engn, Dept Civil & Environm Engn, Dept Mat Sci & Engn, Evanston, IL 60208 USA;

    Univ Illinois, Frederick Seitz Mat Res Lab, Dept Elect & Comp Engn, Urbana, IL 61801 USA;

    Washington Univ, Sch Med, Dept Anesthesiol, Pain Ctr, St Louis, MO 63130 USA;

    Washington Univ, Sch Med, Dept Neurol Surg, St Louis, MO 63110 USA;

    Northwestern Univ, Dept Mat Sci & Engn, Evanston, IL 60208 USA;

    Univ Illinois, Frederick Seitz Mat Res Lab, Dept Elect & Comp Engn, Urbana, IL 61801 USA;

    Northwestern Univ, Dept Mat Sci & Engn, Evanston, IL 60208 USA;

    Univ Illinois, Frederick Seitz Mat Res Lab, Dept Elect & Comp Engn, Urbana, IL 61801 USA;

    Washington Univ, Sch Med, Dept Neurol Surg, St Louis, MO 63110 USA;

    Northwestern Univ, Dept Mech Engn, Dept Civil & Environm Engn, Dept Mat Sci & Engn, Evanston, IL 60208 USA;

    Washington Univ, Sch Med, Dept Anesthesiol, Pain Ctr, St Louis, MO 63130 USA;

    Northwestern Univ, McCormick Sch Engn, Simpson Querrey Inst Nano Biotechnol, Ctr Biointegrated Elect,Dept Mat Sci & Engn,Biome, Evanston, IL 60208 USA;

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  • 正文语种 eng
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  • 关键词

    bioresorbable electronics; bioresorbable polymers; conductive composites; encapsulation; wax;

    机译：生物可吸收电子;生物可吸收聚合物;导电复合材料;包封;蜡;

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