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M13 Virus Aerogels as a Scaffold for Functional Inorganic Materials

机译:M13病毒气凝胶作为功能性无机材料的支架

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摘要

The filamentous M13 viruses are widely used as a bio-template to assemble many different functional structures. In this work, based on its shape anisotropy, reasonable aspect ratio (length to diameter of approximate to 130), and low density, freestanding, bulk 3D aerogels are assembled from M13 for the first time. These ultralight porous structures demonstrate excellent mechanical properties with elastic behavior up to 90% compression. Furthermore, as the genome of M13 virus can be rationally engineered so that proteins on its capsid or ends can specifically bind to various inorganic materials, aerogels made from inorganic-complexed M13 structures with versatile functionalities are also developed. As examples for mono- and multi-component structures, M13-Ru and M13-CoFe2O4 are explored in this work. This method enables the production of a wide variety of freestanding inorganic material aerogels with extensive opportunities for bio-scaffolds, energy storage, thermoelectrics, catalysis, hydrogen storage applications, etc., in the future.
机译:丝状M13病毒被广泛用作组装许多不同功能结构的生物模板。在这项工作中,基于其形状各向异性,合理的长宽比(长径比大约为130)以及低密度,独立的大体积3D气凝胶首次由M13组装而成。这些超轻质多孔结构表现出出色的机械性能,压缩性能高达90%。此外,由于可以对M13病毒的基因组进行合理的工程设计,使得其衣壳或末端的蛋白质可以特异性地与各种无机材料结合,因此还开发了由具有多种功能的无机复合M13结构制成的气凝胶。作为单组分和多组分结构的实例,在这项工作中探索了M13-Ru和M13-CoFe2O4。该方法使得能够生产多种独立的无机材料气凝胶,并在将来为生物支架,能量存储,热电,催化,氢存储应用等提供广泛的机会。

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  • 来源
    《Advanced Functional Materials》 |2017年第4期|1603203.1-1603203.8|共8页
  • 作者单位

    MIT, Dept Elect Engn & Comp Sci, Cambridge, MA 02139 USA|Korea Inst Toxicol, Future Environm Res Ctr, Jinju 52834, South Korea;

    MIT, Dept Mat Sci & Engn, Dept Biol Engn, David H Koch Inst Integrat Canc Res, Cambridge, MA 02139 USA;

    MIT, Dept Mat Sci & Engn, Dept Biol Engn, David H Koch Inst Integrat Canc Res, Cambridge, MA 02139 USA;

    MIT, Dept Mat Sci & Engn, Dept Biol Engn, David H Koch Inst Integrat Canc Res, Cambridge, MA 02139 USA;

    MIT, Dept Elect Engn & Comp Sci, Cambridge, MA 02139 USA;

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  • 原文格式 PDF
  • 正文语种 eng
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  • 关键词

    bio-mediated functional inorganic aerogel; sM13-CoFe2O4 aerogels; M13-Ru aerogels; M13 virus aerogels;

    机译:生物介导的功能性无机气凝胶;sM13-CoFe2O4气凝胶;M13-Ru气凝胶;M13病毒气凝胶;

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