Mussel-Inspired Approach to Constructing Robust Multilayered Alginate Films for Antibacterial Applications

Kim Suyeob; Moon Jung-Mi; Choi Joon Sig; Cho Woo Kyung; Kang Sung Min

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Mussel-Inspired Approach to Constructing Robust Multilayered Alginate Films for Antibacterial Applications

机译：贻贝启发的方法来构建用于抗菌应用的坚固的多层藻酸盐薄膜

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The exceptional mechanical properties of the byssus-the fibrous holdfast of mussels that provides underwater adhesion-have potential applications in medicine and technology. The catechol-Fe3+-catechol interaction underlies the unique properties of mussel byssus and has emerged as a tool for developing functional hybrid materials such as pH-responsive, self-healing gels. Herein, the construction of functional alginate (Alg) film on a solid substrate inspired by mussel byssus is reported. The approach consists of spin-coating-assisted deposition of Alg catechols onto a solid substrate and their subsequent crosslinking via catechol-Fe3+-catechol interactions. This yields robust and multilayered Alg films that are resistant to protein adsorption and suppress bacterial adhesion. This method can be used to create antibacterial films for coating implanted medical devices.

机译：贻贝具有出色的机械性能-贻贝的纤维保持力，可提供水下附着力-在医学和技术领域具有潜在的应用。邻苯二酚与Fe3 +-邻苯二酚的相互作用是贻贝贻贝独特特性的基础，已成为开发功能性杂种材料（例如pH响应型自修复凝胶）的工具。在本文中，据报道在贻贝贻贝的启发下在固体基质上构建功能藻酸盐（Alg）膜。该方法包括将Alg邻苯二酚旋涂辅助沉积到固体基质上，然后通过邻苯二酚-Fe3 +-邻苯二酚相互作用进行交联。这将产生坚固且多层的Alg膜，该膜可抵抗蛋白质吸附并抑制细菌粘附。该方法可用于制造用于涂覆植入式医疗设备的抗菌膜。

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《Advanced Functional Materials》 |2016年第23期|4099-4105|共7页
作者
Kim Suyeob; Moon Jung-Mi; Choi Joon Sig; Cho Woo Kyung; Kang Sung Min;
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Pukyong Natl Univ, Dept Marine Biomat & Aquaculture, Busan 48513, South Korea;

Chungnam Natl Univ, Grad Sch Analyt Sci & Technol, Daejeon 34134, South Korea;

Chungnam Natl Univ, Dept Biochem, Daejeon 34134, South Korea;

Chungnam Natl Univ, Dept Chem, Daejeon 34134, South Korea;

Pukyong Natl Univ, Dept Marine Biomat & Aquaculture, Busan 48513, South Korea;

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1. A facile method to construct hybrid multilayered films as a strong and multifunctional antibacterial coating. [J] . Yuan W, Ji J, Fu J, Journal of biomedical materials research. Part B, Applied biomaterials. . 2008,第2期

机译：一种简便的方法将杂化多层膜构建为坚固的多功能抗菌涂层。
2. A facile method to construct hybrid multilayered films as a strong and multifunctional antibacterial coating. [J] . Yuan W, Ji J, Fu J, Journal of biomedical materials research. Part B, Applied biomaterials. . 2008,第2期

机译：一种简便的方法将杂化多层膜构建为坚固的多功能抗菌涂层。
3. A facile method to construct hybrid multilayered films as a strong and multifunctional antibacterial coating. [J] . Yuan W, Ji J, Fu J, Journal of biomedical materials research. Part B, Applied biomaterials. . 2008,第2期

机译：一种构建杂种多层薄膜作为强型多功能抗菌涂层的容易方法。
4. Effects of mechanism of gelation on physical, mechanical and antibacterial properties of alginate films with oregano essential oil incorporated [C] . R. Villalobos-Carvajal, S. Benavides, J.E. Reyes International congress on engineering and food . 2011

机译：凝胶化机制对牛肝精油的藻酸盐薄膜物理，机械和抗菌性能的影响
5. Application of self-assembled ultrathin film coatings to stabilize enzyme encapsulation and activity in alginate microspheres. [D] . Srivastava, Rohit. 2005

机译：自组装超薄膜涂料在稳定藻酸盐微球中的酶包封和活性中的应用。
6. Mussel-Inspired Approach to Constructing Dual Network Coated Layered Clay for Enhanced Barrier and Antibacterial Properties of Poly(vinyl alcohol) Nanocomposites [O] . Long Mao, Jianda Xie, Huiqing Wu, 2020

机译：贻贝启发方法以构建双网络涂层分层粘土以增强聚（乙烯醇）纳米复合材料的屏障及抗菌性能
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机译：贻贝启发方法，以构建双网络涂层分层粘土，以增强聚（乙烯醇）纳米复合材料的屏障及抗菌性能

Mussel-Inspired Approach to Constructing Robust Multilayered Alginate Films for Antibacterial Applications

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