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Characterizing the burden of disease of particulate matter for life cycle impact assessment

机译:表征颗粒物的疾病负担以进行生命周期影响评估

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Fine particulate air pollution (PM2.5) is a major environmental contributor to human burden of disease and therefore an important component of life cycle impact assessments. An accurate PM2.5 characterization factor, i.e., the impact per kilogram of PM2.5 emitted, is critical to estimating “cradle-to-grave” human health impacts of products and processes. We developed and assessed new characterization factors (disability-adjusted life years (DALY)/kgPM2.5 emitted), or the products of dose-response factors (deaths/kgPM2.5 inhaled), severity factors (DALY/death), and intake fractions (kgPM2.5 inhaled/kgPM2.5 emitted). In contrast to previous health burden estimates, we calculated age-specific concentration- and dose-response factors using baseline data, from 63 US metropolitan areas, consistent with the US study population used to derive the relative risk. We also calculated severity factors using 2010 Global Burden of Disease data. Multiplying the revised PM2.5 dose responses, severity factors, and intake fractions yielded new PM2.5 characterization factors that are higher than previous factors for primary PM2.5 but lower for secondary PM2.5 due to NOx. Multiplying the concentration-response and severity factors by 2005 ambient PM2.5 concentrations yielded an annual US burden of 2,000,000 DALY, slightly lower than previous US estimates. The annual US health burden estimated from PM emissions and characterization factors was 2.2 times higher.
机译:细颗粒空气污染(PM2.5)是造成人类疾病负担的主要环境因素,因此是生命周期影响评估的重要组成部分。准确的PM2.5表征因子,即每千克PM2.5排放的影响,对于估算产品和流程对人类健康的“从摇篮到坟墓”的影响至关重要。我们开发并评估了新的特征因子(残疾调整生命年(DALY)/kgPM2.5排放),或剂量反应因子(死亡/吸入pmPM2.5死亡),严重性因子(DALY /死亡)和摄入量的乘积分数(吸入的kgPM2.5 /排放的kgPM2.5)。与以前的健康负担估算相反,我们使用来自63个美国大城市地区的基线数据计算了特定年龄的浓度和剂量反应因子,与用于得出相对风险的美国研究人群一致。我们还使用2010年全球疾病负担数据计算了严重性因素。将修订后的PM2.5剂量响应,严重性因子和摄入分数相乘,得出新的PM2.5特征因子,由于主要的NO2.5,该因子高于先前的主要PM2.5因素,但低于主要PM2.5的先前因素。将浓度响应和严重性因子乘以2005年的PM2.5浓度,得出美国每年的负担为2,000,000 DALY,略低于美国先前的估计。根据PM排放和特征因素估算的美国年度健康负担高出2.2倍。

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