Optimizing Dynamic T2* MR Imaging for Measurement of Cerebral Blood Flow Using Infusions for Cerebral Blood Volume

G.C. Newman; F.E. Hospod; S.B. Fain; T.D. Cook

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Optimizing Dynamic T2* MR Imaging for Measurement of Cerebral Blood Flow Using Infusions for Cerebral Blood Volume

机译：优化动态T2 * MR成像，通过输注脑血容量来测量脑血流量

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Summary: We describe an approach to measuring cerebral blood flow (CBF) based on independent measurements of cerebral blood volume (CBV) and mean transit time (MTT) with calculation of CBF by using the central volume theorem: CBF = CBV / MTT. This permits optimization of the individual acquisitions and analyses. In particular, measurement of CBV during contrast infusion, rather than simultaneously with MTT from a single bolus, yields values more consistent with those of other methods.

机译：摘要：我们描述了一种基于对脑血体积（CBV）和平均通过时间（MTT）的独立测量，并通过以下方法计算的测量脑血流量（CBF）的方法： sup> CBF，方法是使用中心体积定理：CBF = CBV / MTT。允许对单个采集和分析进行优化。尤其是在对比输注期间测量CBV，而不是与单次推注的MTT同时进行，产生的值与其他方法更一致。

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《American Journal of Neuroradiology》 |2006年第6期|00001239-00001240|共2页
作者
G.C. Newman; F.E. Hospod; S.B. Fain; T.D. Cook;
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Department of Neurology, University of Wisconsin School of Medicine, Madison, Wis|Department of Radiology, University of Wisconsin School of Medicine, Madison, Wis;

Department of Neurology, University of Wisconsin School of Medicine, Madison, Wis;

Department of Radiology, University of Wisconsin School of Medicine, Madison, Wis|Department of Medical Physics, University of Wisconsin School of Medicine, Madison, Wis;

Department of Medical Physics, University of Wisconsin School of Medicine, Madison, Wis;

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6. Optimizing Dynamic T2* MR Imaging for Measurement of Cerebral Blood Flow Using Infusions for Cerebral Blood Volume [O] . G.C. Newman, F.E. Hospod, S.B. Fain, 2006

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Optimizing Dynamic T2* MR Imaging for Measurement of Cerebral Blood Flow Using Infusions for Cerebral Blood Volume

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