Ivermectin and River Blindness

Philip A. Rea; rnVivian Zhang; rnYelena S. Baras

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Ivermectin and River Blindness

机译：伊维菌素与河盲症

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Imagine: itching so intense that you are forced to sleep resting on your knees and elbows; the stigma of persistent rashes, skin discoloration and disfiguring protuberances under your skin. Or, as epitomized by the statue outside the World Health Organization's (WHO) Geneva headquarters depicting a young boy leading a not-so-old blind man with a stick, imagine the prospect of never again seeing your child's face, a child who will likely have to suffer what you are suffering (see Figure 1).lf you can imagine this, you have a sense of what it is like to be afflicted by river blindness and live in a community for which it is a fact of life.

机译：想象一下：瘙痒是如此剧烈，以至于你不得不睡在膝盖和肘部上。持续出现皮疹的污名，皮肤变色和皮肤下的隆起痕迹。或者，如世界卫生组织（世卫组织）日内瓦总部外的塑像所描绘的，该塑像描绘的是一个小男孩用拐杖带领一个不太老的盲人，用一根棍子，想像着再也看不到你孩子的脸的前景了。必须忍受自己所遭受的苦难（见图1）。如果您可以想象得到这一点，您会感觉到被河盲症所困扰，并生活在一个生活中的事实。

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来源
《American Scientist》 |2010年第4期|P.294-303|共10页
作者
Philip A. Rea; rnVivian Zhang; rnYelena S. Baras;
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作者单位

Department of Biology, Carolyn Hoff Lynch Biology Laboratory, University of Pennsylvania;

rnDepartment of Biology, Carolyn Hoff Lynch Biology Laboratory, University of Pennsylvania;

rnDepartment of Biology, Carolyn Hoff Lynch Biology Laboratory, University of Pennsylvania;

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收录信息美国《科学引文索引》(SCI);
原文格式 PDF
正文语种 eng
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1. Modelling the impact of mass administration of ivermectin in the treatment of onchocerciasis (river blindness) [J] . E.O. Omondi, F. Nyabadza, R.J. Smith Cogent Mathematics & Statistics . 2018,第1期

机译：建模伊维菌素大规模给药对盘尾丝虫病（河盲症）的影响
2. Macrofilaricidal Efficacy of Repeated Doses of Ivermectin for the Treatment of River Blindness [J] . MartinWalker, Sébastien D SPion, HanweiFang, Clinical infectious diseases . 2017,第12期

机译：重复剂量的伊维菌素治疗河流盲素的大型疗效
3. Does Increasing Treatment Frequency Address Suboptimal Responses to Ivermectin for the Control and Elimination of River Blindness? [J] . Frempong Kwadwo K., Walker Martin, Cheke Robert A., Clinical infectious diseases . 2016,第11期

机译：增加治疗频率是否能解决对伊维菌素的次优反应，从而控制和消除河盲症？
4. Ivermectin [C] . Meeting of the Joint FAO/WHO Expert Committee on Food Additives . 2015

机译：伊维菌素
5. The Lion's gaze: African river blindness from tropical curiosity to international development. [D] . Bump, Jesse Boardman. 2005

机译：狮子的目光：从热带的好奇心到国际发展的非洲河盲症。
6. Correction: Control Elimination and Eradication of River Blindness: Scenarios Timelines and Ivermectin Treatment Needs in Africa [O] . Young Eun Kim, Jan H. F. Remme, Peter Steinmann, 2015

机译：纠正：控制消除和消除河盲症：非洲的方案时间表和伊维菌素治疗需求
7. Does increasing treatment frequency address sub-optimaludresponses to ivermectin for the control and elimination of river blindness? [O] . Frempong Kwadwo K., Walker Martin, Cheke Robert, 2016

机译：增加治疗频率是否会导致次优 ud伊维菌素对控制和消除河盲症的反应？
8. Placebo-Controlled Double-Blind Trial for the Treatment of Bancroftian Filariasiswith Ivermectin or Diethylcarbamazine [R] . Sabry, M., Gamal, H., El-Masry, N., 1991

机译：安慰剂对照双盲试验用伊维菌素或二乙基咔嗪治疗班氏丝虫病

Ivermectin and River Blindness

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