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首页> 外文期刊>American Journal of Tropical Medicine and Hygiene >TWO CASES OF HANTAVIRUS PULMONARY SYNDROME IN RANDOLPH COUNTY, WEST VIRGINIA: A COINCIDENCE OF TIME AND PLACE?
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TWO CASES OF HANTAVIRUS PULMONARY SYNDROME IN RANDOLPH COUNTY, WEST VIRGINIA: A COINCIDENCE OF TIME AND PLACE?

机译：西弗吉尼亚州兰道夫县的两例汉坦氏肺综合征：时间和地点的重合？

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摘要

Hantavirus pulmonary syndrome (HPS) is caused by an infection with viruses of the genus Hantavirus in the western hemisphere. Rodent hosts of hantaviruses are present throughout the United States. In July 2004, two HPS case-patients were identified in Randolph County, WV: a wildlife science graduate student working locally and a Randolph County resident. We interviewed family members and colleagues, reviewed medical records, and conducted environmental studies at likely exposure sites. Small mammals were trapped, and blood, urine, and tissue samples were submitted to the Centers for Disease Control and Prevention for laboratory analyses. These analyses confirmed that both patients were infected with Monongahela virus, a Sin Nombre hantavirus variant hosted by the Cloudland deer mouse, Peromyscus maniculatus nubiterrae. Other than one retrospectively diagnosed case in 1981, these are the first HPS cases reported in West Virginia. These cases emphasize the need to educate the public throughout the United States regarding risks and prevention measures for hantavirus infection.
机译：汉塔病毒肺综合症（HPS）是由西半球汉塔病毒属病毒感染 引起的。 整个美国范围内都存在啮齿类汉坦病毒的宿主 状态。 2004年7月，在西弗吉尼亚州兰道夫县确定了两名HPS病例患者：一名在当地工作的野生动物科学研究生 和一名兰道夫县居民。我们采访了 家庭成员和同事，检查了病历，并在可能的暴露地点进行了 的环境研究。捕获小型 哺乳动物，并将血液，尿液和组织样品 提交疾病控制与预防中心 进行实验室分析。这些分析证实，两名 病人均感染了Monongahela病毒，该病毒是由Cloudland鹿老鼠Peromyscus maniculatus nubiterrae托管的Sin Nombre hanta病毒变种。除了在1981年进行回顾性诊断的 病例外，这是西弗吉尼亚州首次报告的HPS病例。这些案例强调有必要对全美的公众 进行有关汉坦病毒感染的风险和预防措施的教育。

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