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Two cases of hantavirus pulmonary syndrome in Randolph County, West Virginia: a coincidence of time and place?

机译:西弗吉尼亚州兰道夫县的两例汉坦病毒性肺综合征:时间和地点的巧合?

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Hantavirus pulmonary syndrome (HPS) is caused by an infection with viruses of the genus Hantavirus in the western hemisphere. Rodent hosts of hantaviruses are present throughout the United States. In July 2004, two HPS case-patients were identified in Randolph County, WV: a wildlife science graduate student working locally and a Randolph County resident. We interviewed family members and colleagues, reviewed medical records, and conducted environmental studies at likely exposure sites. Small mammals were trapped, and blood, urine, and tissue samples were submitted to the Centers for Disease Control and Prevention for laboratory analyses. These analyses confirmed that both patients were infected with Monongahela virus, a Sin Nombre hantavirus variant hosted by the Cloudland deer mouse, Peromyscus maniculatus nubiterrae. Other than one retrospectively diagnosed case in 1981, these are the first HPS cases reported in West Virginia. These cases emphasize the need to educate the public throughout the UnitedStates regarding risks and prevention measures for hantavirus infection.
机译:汉坦病毒性肺综合征(HPS)是由西半球汉坦病毒属病毒感染引起的。汉坦病毒的啮齿动物宿主遍布美国。 2004年7月,在西弗吉尼亚州的伦道夫县确定了两名HPS病例患者:一名在当地工作的野生动物科学研究生和一名伦道夫县居民。我们采访了家人和同事,审查了病历,并在可能的暴露地点进行了环境研究。将小型哺乳动物困住,将血液,尿液和组织样本提交疾病控制与预防中心进行实验室分析。这些分析证实,这两名患者均感染了莫农加希拉病毒,莫农加希拉病毒是由Cloudland鹿老鼠Peromyscus maniculatus nubiterrae托管的一种罪恶汉坦病毒。除了1981年的一项回顾性诊断病例外,这是西弗吉尼亚州首次报告的HPS病例。这些案例强调有必要对全美国的汉坦病毒感染的风险和预防措施进行教育。

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