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首页> 外文期刊>American Journal of Tropical Medicine and Hygiene >Transmission Dynamics of Cryptosporidium Infection in a Natural Population of Non-Human Primates at Polonnaruwa, Sri Lanka
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Transmission Dynamics of Cryptosporidium Infection in a Natural Population of Non-Human Primates at Polonnaruwa, Sri Lanka

机译:斯里兰卡波隆纳鲁沃市非人类灵长类动物自然种群中隐孢子虫感染的传播动力学

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摘要

Infections from Cryptosporidium parvum are of interest not only to public health, but also to wildlife conservation, particularly when humans and livestock encroach on nature and thereby increase the risk of cross-species transmissions. To clarify this risk, we used polymerase chain reaction to examine the hypervariable region of the C. parvum 18S rRNA gene in feces from three monkey species. Samples were isolated from regions where disease transmission between monkeys, livestock, and humans was likely (soiled habitat) or unlikely (clean habitat). Monkey individuals, their social groups, and different species shared multiple genotypes/isolates of C. parvum. Ecological and molecular analyses suggested that Cryptosporidium infection among Toque macaques in soiled habitats was mainly the bovine genotype C. parvum. Monkeys inhabiting clean habitat, particularly gray and purple-faced langurs, lacked Cryptosporidium species/types associated with bovines. Livestock apparently was a main source of infection for wild primates.
机译:细小隐孢子虫的感染不仅对公共健康有益,而且对野生生物保护也特别重要,特别是当人类和牲畜侵占自然从而增加 跨物种传播的风险。为了阐明这种风险,我们使用聚合酶链反应来检查来自三个猴子 物种的粪便中小肠弯曲杆菌18S rRNA基因的高变 区域。 。样本是从可能在猴子,牲畜和人类之间传播疾病的地区(污染的栖息地)或不太可能(清洁的栖息地)的区域中分离出来的。猴子个体,其社会 群体和不同物种共享细小隐孢子虫的多种基因型/分离物 。生态和分子分析表明, 污染的生境中的短尾猕猴中的隐孢子虫感染主要是牛基因C. parvum。居住在 干净栖息地的猴子,尤其是灰脸和紫色的叶猴,缺乏与牛有关的 隐孢子虫种类/类型。显然,畜牧 是野生灵长类动物的主要感染源。

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    Department of Biochemistry and Molecular Biology, Universityof Georgia, Athens, Georgia Josephine Bay Paul Center, MarineBiological Laboratory, Woods Hole, MassachusettsGlobal InfectiousDisease Program, Marine Biological Laboratory, Woods Hole, Massachusetts;

    Department of Biochemistry and Molecular Biology, Universityof Georgia, Athens, Georgia;

    Association for the Conservationof Primate Diversity, Kandy, Sri Lanka;

    Institute of FundamentalStudies, Sri Lanka;

    Department of Conservation Biology, SmithsonianNational Zoological Park, Washington, District of Columbia;

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