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Influence du lanreotide sur la concentration serique de prolactine chez les patients atteints de tumeurs somato-lactotropes

机译:兰瑞肽对促生长性肿瘤患者血清催乳素浓度的影响

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摘要

Acromegaly is a disease caused by a pituitary tumor (somatotropinoma) or by ec-topic secretion of GH or IGF-1. About 15 % of tumors secrete not only GH but PRL as well. Last time a lanreotide and an octreotide (the somatostatine analogues) are useful in the therapy of acromegaly. We observed the influence of the lanreotide on GH and prolactin. We noticed that the lanreotide caused not only serum level reduction of a growth hormone but also prolactine in patients with mixed pituitary tumors.
机译:肢端肥大症是由垂体瘤(促生长素瘤)或GH或IGF-1的异位分泌引起的疾病。大约15%的肿瘤不仅分泌GH,而且还分泌PRL。上一次,兰瑞肽和奥曲肽(生长抑素类似物)可用于肢端肥大症的治疗。我们观察到了兰瑞肽对GH和催乳激素的影响。我们注意到,兰瑞肽不仅导致混合性垂体瘤患者的血清激素水平降低,还导致催乳素水平下降。

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