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How versioning of terminology systems can be supported by ontological models - a case study on TNM tumor classification

机译：本体模型可以支持术语系统版本控制方式 - 一种关于TNM肿瘤分类的案例研究

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摘要

The TNM classification (Tumor-Node-Metastasis) is the most important coding scheme used to stage tumors based on size and location. Its coding rules may change across different TNM versions, such that the same tumor is represented by different codes in different versions. We present an ontology-based modular architecture for the management of TNM, using the coding rules for pancreas tumors in the considerably different TNM versions 7 and 8 in order to demonstrate how mappings (in the sense of re-classification) between TNM versions can be supported. To enable re-classification of tumor instances between TNM versions, mapping ontologies were created. This work describes two version mapping approaches, one using SWRL rules and the other intermediate classes representing the mapping criteria between the TNM versions. We show that tumor instances with defined characteristics were correctly classified in different TNM versions. In addition, ontological inconsistencies in classification systems based on informal text labels and possible conversion problems due to different categorization criteria in different TNM versions are demonstrated.
机译：TNM分类（肿瘤节点转移）是最重要的编码方案，用于基于尺寸和位置阶段延期的肿瘤。其编码规则可能跨不同的TNM版本改变，使得相同的肿瘤由不同版本中的不同代码表示。我们介绍了一种基于本体的模块化架构，用于管理TNM，在相当不同的TNM版本7和8中，使用胰腺肿瘤的编码规则，以便演示TNM版本之间的映射（在重新分类中的重新分类）支持的。要在TNM版本之间重新分类TNM版本之间，请创建映射本体。这项工作描述了两个版本映射方法，一个使用SWRL规则和表示TNM版本之间的映射条件的其他中间类。我们表明，在不同的TNM版本中正确分类了具有定义特征的肿瘤实例。此外，还证明了基于非正式文本标签的分类系统和不同的TNM版本中可能的转换问题的本体论不一致。

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  • 来源
    《Applied ontology》 |2020年第1期|41-60|共20页
  • 作者

    Zabka Susanne; Schulz Stefan; Brunner Oliver; Boeker Martin;

  • 作者单位

    Institute for Medical Biometry and Medical InformaticsandComprehensive Cancer Center Faculty of Medicine and Medical Center University of Freiburg;

    Institute of Medical Informatics Statistics and Documentation Medical University of Graz;

    Department of Computer Science University of Freiburg;

    Institute for Medical Biometry and Medical InformaticsandComprehensive Cancer Center Faculty of Medicine and Medical Center University of Freiburg;

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  • 正文语种 eng
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  • 关键词

    Ontology; TNM classification; pancreas tumor; SWRL rules; TNM-O; mapping;

    机译：本体;TNM分类;胰腺肿瘤;SWRL规则：TNM-O映射;

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