...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Archives of Pharmacal Research >Antimicrobial peptides: Their physicochemical properties and therapeutic application
【24h】

Antimicrobial peptides: Their physicochemical properties and therapeutic application

机译：抗菌肽：其理化性质和治疗应用

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Antibiotic resistance has become a global public health problem, thus there is a need to develop a new class of antibiotics. Natural antimicrobial peptides have got an increasing attention as potential therapeutic agents. Antimicrobial peptides are small cationic peptides with broad antimicrobial activity. They can serve as critical defense molecules protecting the host from the invasion of bacteria. Even though they possess a different mode of action compared to traditional antibiotics, antimicrobial peptides couldn’t go into the drug markets because of problems in application such as toxicity, susceptibility to proteolysis, manufacturing cost, size, and molecular size. Nevertheless, antimicrobial peptides can be new hope in developing novel, effective and safe therapeutics without antibiotic resistance. Thus, it is necessary to discover new antimicrobial sources in nature and study their structures and physicochemical properties more in depth.
机译：抗生素抗性已经成为全球公共卫生问题，因此需要开发新型的抗生素。天然抗菌肽作为潜在的治疗剂已受到越来越多的关注。抗菌肽是具有广泛抗菌活性的小阳离子肽。它们可以用作保护宿主免受细菌入侵的关键防御分子。尽管抗菌肽与传统抗生素相比具有不同的作用方式，但由于应用中的问题，例如毒性，蛋白水解敏感性，制造成本，尺寸和分子大小，抗菌肽无法进入药物市场。然而，抗菌肽在开发无抗生素耐药性的新型，有效和安全的疗法方面可能是新的希望。因此，有必要在自然界中发现新的抗微生物来源，并更深入地研究其结构和理化特性。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号