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A Passively Controlled Biventricular Support Device

机译：被动控制的双心室支持装置

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摘要

Clinical studies have reported the balancing of pump outputs to be a serious control issue for rotary biventricular support (BiVS) systems. Poor reliability of long-term, blood immersed pressure sensors encouraged the development of a new control strategy to improve their viability. A rotary BiVS device was designed and constructed with a mechanical passive controller to autoregulate pump outputs to emulate the native baroreceptor response. In vitro testing in a dual circuit, hydraulic mock circulation loop showed that the prototype was able to maintain arterial pressures when subjected to sudden induced hemodynamic destabilization. However, inlet suction was observed when sudden simulated hypertension briefly reduced venous return to the cannulated ventricle. The results have encouraged further development of the device as a means to create an inherently stable, fully passive biventricular support device.
机译：临床研究表明，泵输出的平衡对于旋转双心室支持（BiVS）系统是一个严重的控制问题。长期浸入血液中的压力传感器的可靠性差，鼓励开发新的控制策略以提高其生存能力。设计并构造了带有机械无源控制器的旋转BiVS设备，以自动调节泵的输出，以模拟自然的压力感受器响应。在双回路液压模拟循环回路中进行的体外测试表明，该原型机在遭受突然引起的血流动力学不稳定时能够保持动脉压。但是，当突然出现的模拟高血压短暂减少静脉回流至插管心室时，观察到入口抽吸。结果鼓励了该装置的进一步开发，以作为一种创建固有稳定的，完全被动的双心室支撑装置的手段。

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  • 来源
    《Artificial Organs》 |2010年第6期|p.473-480|共8页
  • 作者

    Nicholas Richard Gaddum; Daniel Lee Timms; Mark John Pearcy;

  • 作者单位

    School of Engineering Systems and Medical Device Domain, Institute of Health and Biomedical Innovation, Queensland University of Technology, and;

    Department of Thoracic Medicine, The Prince Charles Hospital and the Critical Care Research Group, The Prince Charles Hospital, Brisbane, Australia;

    School of Engineering Systems and Medical Device Domain, Institute of Health and Biomedical Innovation, Queensland University of Technology, and;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    Passive control; Biventricular support; Rotary pump; Mock circulation; Baroreceptor response;

    机译：被动控制;双心室支持;旋转泵;模拟循环;压力感受器反应;

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