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Twenty-year outcome for individuals with autism and average or near-average cognitive abilities

机译:具有自闭症和平均或近乎平均认知能力的人的20年结局

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摘要

Previous studies found substantial variability in adult outcome for people with autism whose cognitive functioning was within the near-average and average ranges. This study examined adult outcome for 41 such individuals (38 men and 3 women) originally identified through an epidemiological survey of autism in Utah. Mean age at the time of their previous cognitive assessment was 7.2 years (SD=4.1, range=3.1-25.9 years) and at follow-up was 32.5 years (SD=5.7 years, range=22.3-46.4 years). Outcome measures included standardized assessments of diagnostic status, cognitive ability, and adaptive behavior. Additional information collected concerned demographic variables, indicators of independence, social relationships, medical and psychiatric conditions, and social service use. Outcomes for this sample were better than outcomes described in previous work on individuals with similar cognitive functioning. For example, half of the participants were rated as Very Good or Good on a global outcome measure. As in previous studies, there was considerable variability in measured cognitive ability over time. Over half of the sample had large gains or losses of cognitive ability of greater than 1 standard deviation. Cognitive gain was associated with better outcome, as was better adaptive functioning. While all participants had baseline IQs in the nonimpaired range, there was limited evidence to support the use of other early childhood variables to predict adult outcome.
机译:先前的研究发现,自闭症患者的认知功能在接近平均水平和平均水平的范围内,其成人结局具有很大差异。这项研究检查了最初通过犹他州自闭症流行病学调查确定的41名此类患者(38名男性和3名女性)的成人结局。他们之前的认知评估时的平均年龄为7.2岁(SD = 4.1,范围= 3.1-25.9岁),随访时的平均年龄为32.5岁(SD = 5.7岁,范围= 22.3-46.4岁)。结果措施包括诊断状态,认知能力和适应性行为的标准化评估。收集的其他信息涉及人口统计学变量,独立性指标,社会关系,医疗和精神病状况以及社会服务使用情况。该样本的结果优于先前关于具有相似认知功能的个体的工作中描述的结果。例如,根据全球成果评估,一半的参与者被评为非常好或好。与以前的研究一样,测得的认知能力随时间变化很大。超过一半的样本具有大于1个标准差的认知能力大幅获胜或丧失。认知增益与较好的预后相关,适应性功能也更好。尽管所有参与者的基线智商都在未受损范围内,但仅有有限的证据支持使用其他早期儿童变量来预测成人结局。

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  • 来源
    《Autism Research》 |2009年第2期|109-118|共10页
  • 作者单位

    Department of Psychiatry, University of Utah, Salt Lake City, Utah|Department of Educational Psychology, University of Utah, Salt Lake City, Utah;

    Department of Psychiatry, University of Utah, Salt Lake City, Utah|The Brain Institute, University of Utah, Salt Lake City, Utah;

    Department of Psychiatry, McGill University, Montreal, Quebec, Canada;

    Department of Educational Psychology, University of Utah, Salt Lake City, Utah;

    Department of Psychiatry, University of Utah, Salt Lake City, Utah;

    Department of Educational Psychology, University of Utah, Salt Lake City, Utah;

    Department of Educational Psychology, University of Utah, Salt Lake City, Utah;

    Carmen B. Pingree Center for Children with Autism, Salt Lake City, Utah;

    Neuropsychiatric Institute, Los Angeles Medical School, University of California, Los Angeles, California;

    Yale Child Study Center, Yale University School of Medicine, New Haven, Connecticut;

    Department of Psychiatry, University of Utah, Salt Lake City, Utah;

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