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Molecular Phylogenetic Analysis of Zebra Finch Basic Helix-Loop-Helix Transcription Factors

机译:斑马雀科基本螺旋-环状-螺旋转录因子的分子系统发育分析

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The zebra finch (Taeniopygia guttata) is an established organism for developmental, behavioral, and neurological research. In this study, we conducted a genomewide survey using the zebra finch genome project databases and identified 86 bHLH sequences in silico in the zebra finch genome. Phylogenetic analysis revealed that 85 proteins belong to 38 families with 29, 18, 18, 3, 11, and 6 bHLH members in supergroups A, B, C, D, E, and F, respectively. One orphan member belonged to none of these groups. Comparisons of zebra finch with chicken and human bHLH repertoires suggested that both humans and birds have a number of lineage-specific bHLH members. Chromosome distribution patterns and phylogenetic analysis suggest that the zebra finch bHLH members should have arisen through gene duplication. This study provides useful information for further research using zebra finch as a model system.
机译:斑马雀科(Taeniopygia guttata)是用于发育,行为和神经学研究的成熟生物。在这项研究中,我们使用斑马雀科基因组计划数据库进行了全基因组调查,并在斑马雀科基因组的计算机中鉴定了86个bHLH序列。系统发育分析表明,超组A,B,C,D,E和F中有85种蛋白质分别属于38个家族,分别具有29、18、18、3、11和6个bHLH成员。一位孤儿不属于这些群体。斑马雀与鸡和人类bHLH谱系的比较表明,人类和鸟类都有许多特定于谱系的bHLH成员。染色体分布模式和系统发育分析表明,斑马雀bHLH成员应该通过基因复制而产生。这项研究为使用斑马雀科作为模型系统的进一步研究提供了有用的信息。

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