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首页> 外文期刊>Biochemical Genetics >Polymorphism in a Microsatellite of the Acrp30 Gene and Its Association with Growth Traits in Goats
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Polymorphism in a Microsatellite of the Acrp30 Gene and Its Association with Growth Traits in Goats

机译：Acrp30基因微卫星中的多态性及其与山羊生长特性的关联。

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摘要

Acrp30 plays a critical role in the regulation of glucose and lipid homeostasis. In this study, polymorphism of the Acrp30 gene was detected by PCR-SSCP and DNA sequencing methods in 321 individuals from three goat breeds, and the association of Acrp30 gene polymorphism with growth traits in the three goat breeds was analyzed. A novel insert/deletion (GT)5 microsatellite sequence was detected in the 5′ flanking region of the gene. Three genotypes (AA, AB, and BB) were found in three breeds. There was moderate genetic diversity in the locus in the analyzed populations. Significant associations were observed between the genotypes of the locus and growth traits in the Boer goat population. The chest circumference of individuals with genotype BB was significantly greater than that of individuals with genotype AA.
机译：Acrp30在调节葡萄糖和脂质体内稳态中起关键作用。本研究通过PCR-SSCP和DNA测序方法检测了三个山羊品种的321个个体的Acrp30基因多态性，并分析了Acrp30基因多态性与三个山羊品种的生长性状的相关性。在该基因的5'侧翼区域检测到一个新的插入/缺失（GT） 5 微卫星序列。在三个品种中发现了三种基因型（AA，AB和BB）。在所分析的种群中，基因座具有中等的遗传多样性。在布尔山羊种群中，基因座的基因型与生长性状之间存在显着的关联。 BB基因型个体的胸围明显大于AA基因型个体。

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