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首页> 外文期刊>Biochemical Genetics >Genetic Diversity of the Melanocortin 4 Receptor (MC4R) Gene and its Association with Slaughter Traits in the Landes Goose
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Genetic Diversity of the Melanocortin 4 Receptor (MC4R) Gene and its Association with Slaughter Traits in the Landes Goose

机译:黑雁皮层皮质激素4受体(MC4R)基因的遗传多样性及其与屠宰性状的关联。

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摘要

Melanocortin 4 receptor (MC4R) plays a crucial part in regulating feeding behavior in humans and rodents. We detected two single nucleotide polymorphisms (SNPs; c.108G → A and c.627C → T) in the goose MC4R gene and genotyped 94 Landes geese for association analysis with several carcass traits. Significant associations (P < 0.05) were obtained for c.108G → A with carcass weight, breast muscle percentage, and leg muscle percentage, and for c.627C → T with body weight, carcass weight, semi-eviscerated weight, and eviscerated weight. We re-constructed haplotypes based on the two SNPs and analyzed diplotypes in association with carcass traits, obtaining significant associations with several of the traits. These results suggest that polymorphisms in the MC4R gene could have effects on carcass traits in Landes geese. More study is required to confirm these results.
机译:黑皮质素4受体(MC4R)在调节人类和啮齿动物的进食行为中起着至关重要的作用。我们在鹅MC4R基因中检测到两个单核苷酸多态性(SNPs; c.108G→A和c.627C→T),并对94个Landes鹅进行了基因分型,以与几种car体性状进行关联分析。对于c.108G→A与car体重量,胸肌百分比和腿部肌肉百分比,以及对于c.627C→T与体重,car体重量,半内脏重量和内脏重量显着相关(P <0.05) 。我们基于两个SNP重构单倍型,并分析了与car体性状相关的双倍型,获得了与多个性状的显着关联。这些结果表明,MC4R基因的多态性可能对Landes鹅的car体性状有影响。需要更多的研究来证实这些结果。

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