Molecular-genetic mechanisms of cornea morphogenesis

Panova I. G.; Markitantova Yu V.; Smirnova Yu A.; Zinovieva R. D.

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Molecular-genetic mechanisms of cornea morphogenesis

机译：角膜形态发生的分子遗传机制

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In this paper, we analyzed our own results and published data on the expression of regulatory genes encoding transcription factors Pax6/PAX6, Pitx2/PITX2, Fox1/FOXC1, Prox1/PROX1, Oct4/OCT4, Nanog/NANOG, and TGF beta 2 signaling protein during morphogenesis of the cornea in vertebrates. We considered the results obtained for the cornea of model animals, primarily mice, and human fetal cornea. The main possibility of establishing common mechanisms of eye development in vertebrates in health and disease is comparative studies of eye morphogenesis of humans and animal models.

机译：在本文中，我们分析了自己的结果并发表了有关编码转录因子Pax6 / PAX6，Pitx2 / PITX2，Fox1 / FOXC1，Prox1 / PROX1，Oct4 / OCT4，Nanog / NANOG和TGF beta 2信号转导的调控基因表达的数据。脊椎动物角膜形态发生过程中的蛋白质我们考虑了从模型动物（主要是小鼠）和人类胎儿角膜获得的结果。在健康和疾病中建立脊椎动物眼睛发育的常见机制的主要可能性是人类和动物模型的眼睛形态发生的比较研究。

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《Biology Bulletin》 |2015年第2期|83-91|共9页
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Panova I. G.; Markitantova Yu V.; Smirnova Yu A.; Zinovieva R. D.;
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Russian Acad Sci, Koltzov Inst Dev Biol, Moscow 119334, Russia;

Russian Acad Sci, Koltzov Inst Dev Biol, Moscow 119334, Russia;

Russian Acad Sci, Koltzov Inst Dev Biol, Moscow 119334, Russia;

Russian Acad Sci, Koltzov Inst Dev Biol, Moscow 119334, Russia;

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Molecular-genetic mechanisms of cornea morphogenesis

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