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首页> 外文期刊>Biology Bulletin >Role Of A Regulatory Protein From The Bovine Cornea In Activation Of Cell Sources Of Corneal Regeneration In Vitro
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Role Of A Regulatory Protein From The Bovine Cornea In Activation Of Cell Sources Of Corneal Regeneration In Vitro

机译:牛角膜调节蛋白在体外激活角膜再生细胞来源中的作用

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摘要

A highly purified regulatory protein isolated from the bovine cornea (RPC) was tested for the effect on the rat and newt corneas in vitro under different culture conditions. In the newt cornea, RPC stimulated lim-bus epithelial cells in roller cultures and cells in the basal layer of corneal epithelium in both roller and stationary cultures. In roller cultures of the rat cornea, RPC had no effect on weakly differentiated limbus cells but stimulated progenitor cells of the basal cornea layer to differentiation into definitive epithelial cells. In stationary cultures, RPC did not activate the involvement of cells in regeneration of the rat corneal tissue.
机译:测试了从牛角膜(RPC)分离出的高度纯化的调节蛋白在不同培养条件下对大鼠和new角膜的影响。在the角膜中,RPC刺激了滚动培养中的lim-bus上皮细胞以及滚动培养和固定培养中角膜上皮基底层的细胞。在大鼠角膜的滚轴培养中,RPC对弱分化的角膜缘细胞没有作用,但刺激了基底角膜层的祖细胞分化为定形上皮细胞。在固定培养中,RPC不会激活细胞参与大鼠角膜组织再生。

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