EPR Spectrometric Estimation of the Distribution of Intravenously Injected Nanodiamonds in Mice

Inzhevatkin E. V.; Baron A. V.; Maksimov N. G.; Volkova M. B.; Puzyr A. P.; Bondar V. S.

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EPR Spectrometric Estimation of the Distribution of Intravenously Injected Nanodiamonds in Mice

机译：epr光谱估计小鼠静脉内注射纳米金刚石的分布

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The distribution in mice of intravenously injected modified nanodiamonds (MNDs) obtained by detonation synthesis was studied using electron paramagnetic resonance (EPR) spectrometry. It has been shown that 2.5 h after MND injection into the tail vein of mice, the nanoparticles accumulate mainly in the lungs and liver of animals; much smaller amounts of nanoparticles were found in the kidneys and heart. The presence of MNDs in the samples of blood, spleen, brain, and thigh muscles of mice was not detected within the sensitivity of the method used.

机译：使用电子顺磁共振（EPR）光谱法研究了通过爆轰合成获得的静脉内注射的修饰纳米胺（MNDS）小鼠的分布。已经表明，在MND注射到小鼠尾静脉后2.5小时，纳米颗粒主要积聚在动物的肺部和肝脏;在肾脏和心脏中发现了要少量的纳米颗粒。在使用的方法的灵敏度内未检测到小鼠的血液，脾，脑和大腿肌样品中的MNDS的存在。

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《Biology Bulletin》 |2019年第3期|277-283|共7页
作者
Inzhevatkin E. V.; Baron A. V.; Maksimov N. G.; Volkova M. B.; Puzyr A. P.; Bondar V. S.;
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Russian Acad Sci Int Sci Ctr Studies Extreme States Organism Fed Res Ctr Krasnoyarsk Sci Ctr Siberian Branch Akademgorodok 50 Krasnoyarsk 660036 Russia;

Russian Acad Sci Siberian Branch Inst Biophys Fed Res Ctr Krasnoyarsk Sci Ctr Akademgorodok 50-50 Krasnoyarsk 660036 Russia|Siberian Fed Univ Pr Svobodnyi 79 Krasnoyarsk 660041 Russia;

Russian Acad Sci Inst Chem & Chem Technol Fed Res Ctr Krasnoyarsk Sci Ctr Siberian Branch Akademgorodok 50-24 Krasnoyarsk 660036 Russia;

Russian Acad Sci Int Sci Ctr Studies Extreme States Organism Fed Res Ctr Krasnoyarsk Sci Ctr Siberian Branch Akademgorodok 50 Krasnoyarsk 660036 Russia|Siberian Fed Univ Pr Svobodnyi 79 Krasnoyarsk 660041 Russia;

Russian Acad Sci Siberian Branch Inst Biophys Fed Res Ctr Krasnoyarsk Sci Ctr Akademgorodok 50-50 Krasnoyarsk 660036 Russia;

Russian Acad Sci Siberian Branch Inst Biophys Fed Res Ctr Krasnoyarsk Sci Ctr Akademgorodok 50-50 Krasnoyarsk 660036 Russia;

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1. EPR Spectrometric Estimation of the Distribution of Intravenously Injected Nanodiamonds in Mice [J] . Inzhevatkin E. V., Baron A. V., Maksimov N. G., Biology Bulletin . 2019,第3期

机译：EPR光谱估计小鼠静脉注射纳米金刚石的分布。
2. Erratum to: Absorption, distribution and excretion of intravenously injected 68Ge/ 68Ga generator eluate in healthy rats, and estimation of human radiation dosimetry [J] . Anu Autio, Helena Virtanen, Tuula Tolvanen, EJNMMI Research . 2016,第1期

机译：勘误：健康大鼠静脉内注射 68 Ge / 68 Ga生成物洗脱液的吸收，分布和排泄，以及人体辐射剂量法的估算
3. Absorption, distribution and excretion of intravenously injected 68Ge/ 68Ga generator eluate in healthy rats, and estimation of human radiation dosimetry [J] . Anu Autio, Helena Virtanen, Tuula Tolvanen, EJNMMI Research . 2015,第4期

机译：静脉内注射的吸收，分布和排泄静脉内注射的 68 Ge / 68℃/ sup> Ga发电机在健康大鼠中洗脱液，以及人辐射剂量测定的估算
4. Biodistribution and Toxicity Study of Titanium Dioxide Nanoparticles of Different Sizes after Intravenous Injection in Mice [C] . Jie Fang, Lulu Yuan, Chenjie Yao International Conference on Applied Sciences, Engineering and Technology . 2014

机译：小鼠静脉注射后不同尺寸二氧化钛纳米粒子的生物分布和毒性研究
5. Changing the Pancreatic Cancer Treatment Paradigm: Developing Clostridium novyi as an Intravenously Injectable Solid-State Tumor Therapeutic [D] . Dailey, Kaitlin Marie. 2020

机译：改变胰腺癌治疗范式：将Novyi显影为静脉内注射的固态肿瘤治疗方法
6. Erratum to: Absorption distribution and excretion of intravenously injected 68Ge/68Ga generator eluate in healthy rats and estimation of human radiation dosimetry [O] . Anu Autio, Helena Virtanen, Tuula Tolvanen, 2016

机译：勘误：健康大鼠静脉注射68Ge / 68Ga生成物洗脱液的吸收分布和排泄并估算人体辐射剂量
7. Erratum to: Absorption, distribution and excretion of intravenously injected Ge/Ga generator eluate in healthy rats, and estimation of human radiation dosimetry [O] . 2016

机译：勘误到：健康大鼠中静脉注射Ge / Ga生成物洗脱液的吸收，分布和排泄，以及人体辐射剂量法的估算

EPR Spectrometric Estimation of the Distribution of Intravenously Injected Nanodiamonds in Mice

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