• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Biology Bulletin >Effects of Limonium effusum Ethanol Extracts on Cell Proliferation and Mutagenicity
【24h】

Effects of Limonium effusum Ethanol Extracts on Cell Proliferation and Mutagenicity

机译：紫檀乙醇提取物对细胞增殖和致突变性的影响

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Limonium plants have commonly used as antibacterial, styptical, anti-swelling agent, digestive system regulator, anticarcinogenic, and antiviral in alternative medicine. Beside this, different extracts of Limonium plants have mutagenic, cytotoxic and genotoxic effects. Different parts of Limonium effusum (Boiss.) Kuntze ethanol extracts were used to determine the mutagenic and cytotoxic effects. Ames test was carried out with Salmonella typhimurium TA98, and TA100 strains to determine the mutagenicity. Ames test results showed that root 1000 mu g/plate of plant has mutagenic effect and root extracts have weak mutagenicity with TA98 strain. MTT test was carried out with MDBK (Madin-Darby Bovine Kidney) cells to determine the cytotoxicity. Cytotoxicity results showed that root 50, 25, 12.5 and 6.25 mu g/mL extracts were increased the proliferation rates in 24 h treatment. All doses of root extracts decreased the rates in 96 h. All concentrations of stem decreased the proliferation rates in 96 h. Leaf extracts increased the rates in 24 h but decreased in 48, 72, and 96 h.
机译：紫砂植物通常用作抗菌，无论是抗膨胀剂，消化系统调节剂，抗遗传学和抗病毒中的替代药物。除此之外，贴膜植物的不同提取物具有诱变，细胞毒性和遗传毒性作用。利用紫杉醇的不同部位（Boiss。）kuntze乙醇提取物用于确定诱变和细胞毒性效果。 Ames试验用沙门氏菌Typhimurium Ta98和TA100菌株进行，以确定致突变性。 AMES测试结果表明，根1000μg植物具有致致突变效果，根提取物具有较弱的突变性与TA98菌株。 MTT测试用MDBK（Madin-Darby牛肾）细胞进行，以确定细胞毒性。细胞毒性结果表明，24小时治疗中，根系50,25,12.5和6.25μg/ mL提取物增加了增殖率。所有剂量的根提取物降低了96小时的速率。所有浓度的茎均为96小时的增殖率降低。叶提取物增加了24小时的速率，但在48,72和96小时内降低。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号