Breath ammonia and ethanol increase in response to a high protein challenge

Spacek Lisa A.; Mudalel Matthew L.; Lewicki Rafal; Tittel Frank K.; Risby Terence H.; Stoltzfus Jill; Munier Joseph J.; Solga Steven F.

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Breath ammonia and ethanol increase in response to a high protein challenge

机译：应对高蛋白挑战，呼吸中的氨和乙醇增加

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Quantifying changes in ammonia and ethanol in blood and body fluid assays in response to food is cumbersome. We used breath analysis of ammonia, ethanol, hydrogen (an accepted standard of gut transit) and acetone to investigate gastrointestinal physiology. In 30 healthy participants, we measured each metabolite serially over 6 h in control and high protein trials. Two-way repeated measures ANOVA compared treatment (control versus intervention), change from baseline to maximum and interaction of treatment and time change. Interaction was significant for ammonia (p<0.0001) and hydrogen (p <0.0001). We describe the dynamic measurement of multiple metabolites in response to an oral challenge.

机译：量化血液和体液中氨和乙醇的变化以响应食物是很麻烦的。我们使用氨气，乙醇，氢气（肠道运输的公认标准）和丙酮进行呼吸分析，以研究胃肠道生理。在30名健康参与者中，我们在对照和高蛋白试验中连续6小时测量了每种代谢产物。双向重复测量ANOVA比较治疗（对照与干预），从基线到最大值的变化以及治疗和时间变化的相互作用。氨（p <0.0001）和氢（p <0.0001）的相互作用显着。我们描述了对口服挑战的多种代谢物的动态测量。

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来源
《Biomarkers》 |2015年第8期|149-156|共8页
作者
Spacek Lisa A.; Mudalel Matthew L.; Lewicki Rafal; Tittel Frank K.; Risby Terence H.; Stoltzfus Jill; Munier Joseph J.; Solga Steven F.;
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作者单位

Johns Hopkins Univ, Sch Med, Dept Med, Baltimore, MD 21205 USA;

Bethlehem Breath Res, Bethlehem, PA USA;

Rice Univ, Dept Elect & Comp Engn, Houston, TX 77251 USA;

Rice Univ, Dept Elect & Comp Engn, Houston, TX 77251 USA;

Johns Hopkins Univ, Dept Environm Hlth Sci, Bloomberg Sch Publ Hlth, Baltimore, MD 21205 USA;

Johns Hopkins Univ, Dept Environm Hlth Sci, Bloomberg Sch Publ Hlth, Baltimore, MD 21205 USA;

Bethlehem Breath Res, Bethlehem, PA USA;

St Lukes Univ Hosp, Bethlehem, PA USA;

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正文语种 eng
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关键词
Acetone; ammonia; breath metabolites; ethanol; gastrointestinal physiology;

机译：丙酮;氨;呼吸代谢产物;乙醇;胃肠道生理学;

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1. Repeated Measures of Blood and Breath Ammonia in Response to Control, Moderate and High Protein Dose in Healthy Men [J] . Lisa A. Spacek, Arthur Strzepka, Saurabh Saha, Scientific reports. . 2018,第1期

机译：反复措施血液和呼吸氨响应于对照，中度和高蛋白剂量在健康男性中
2. Increase of club cell (Clara) protein (CC16) in plasma and urine after exercise challenge in asthmatics and healthy controls, and correlations to exhaled breath temperature and exhaled nitric oxide [J] . TufvessonE., SvenssonH., AnkerstJ., Respiratory medicine . 2013,第11期

机译：哮喘患者和健康对照者运动后血浆和尿液中俱乐部细胞（Clara）蛋白（CC16）的增加，以及呼气温度和呼出气一氧化氮的相关性
3. Increase of club cell (Clara) protein (CC16) in plasma and urine after exercise challenge in asthmatics and healthy controls, and correlations to exhaled breath temperature and exhaled nitric oxide [J] . TufvessonE., SvenssonH., AnkerstJ., Respiratory medicine . 2013,第11期

机译：在哮喘和健康对照中运动攻击后血浆和尿液中血浆细胞（CC16）的增加，以及呼出呼吸温度和呼出的一氧化氮的相关性
4. INCREASING PROTEIN EXTRACTION YIELD FROM DUCKWEED (Lemna obscura) WITH AN AMMONIA TREATMENT [C] . L. Urribarri, J. Rios, A. Ferrer Proceedings of an International Conference . 2010

机译：用氨治疗增加来自浮萍（Lemna Obscura）的蛋白质提取产量
5. UV-C irradiation of Yarrowia lipolytica NRRL YB-567 to produce mutant strains with an increased production of ammonia and oil from protein substrates. [D] . Lindquist, Mitchell R. 2016

机译：解脂耶氏酵母NRRL YB-567的UV-C辐照产生突变菌株，从蛋白质底物产生的氨和油的产量增加。
6. Repeated Measures of Blood and Breath Ammonia in Response to Control Moderate and High Protein Dose in Healthy Men [O] . Lisa A. Spacek, Arthur Strzepka, Saurabh Saha, -1

机译：对健康男性控制中度和高蛋白剂量的血液和呼吸氨的重复测量
7. Repeated Measures of Blood and Breath Ammonia in Response to Control, Moderate and High Protein Dose in Healthy Men [O] . Lisa A. Spacek, Arthur Strzepka, Saurabh Saha, 2018

机译：反复措施血液和呼吸氨响应于对照，中度和高蛋白剂量在健康男性中

Breath ammonia and ethanol increase in response to a high protein challenge

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