Trefoil Factor 1 as a marker of mucosal damage of the gastrointestinal tract in children with sepsis

Jiri Zurek; Michal Fedora

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Trefoil Factor 1 as a marker of mucosal damage of the gastrointestinal tract in children with sepsis

机译：三叶因子1是脓毒症患儿胃肠道黏膜损伤的标志

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Intestinal ischemia and reperfusion is a common pathway for many diseases in children. The objective of our study was an analysis of Trefoil factor 1 levels dynamics in patients with SIRS or septic condition during a 5-day period. Analysis of TFF1 levels dynamics revealed that TFF1 levels kept steady state during the 5-day period. TFF1 levels were similar in patients with SIRS, sepsis and severe sepsis. Significantly higher levels of TFF1 were in patients with septic shock and MODS.

机译：肠缺血和再灌注是许多儿童疾病的常见途径。我们研究的目的是分析5天内SIRS或脓毒症患者的三叶因子1水平动态。 TFF1水平动态分析显示，TFF1水平在5天期间保持稳定状态。 SIRS，脓毒症和严重脓毒症患者的TFF1水平相似。败血性休克和MODS患者的TFF1水平显着升高。

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《Biomarkers》 |2013年第4期|338-342|共5页
作者
Jiri Zurek; Michal Fedora;
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作者单位

Department of Anesthesia and Intensive Care, University Children's Hospital, Czech Republic;

Department of Anesthesia and Intensive Care, University Children's Hospital, Czech Republic;

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正文语种 eng
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关键词
Children; gut; mortality; sepsis; trefoil factor;

机译：儿童;肠死亡;败血症三叶因子;

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1. Trefoil factor 3 as a marker of intestinal cell damage during sepsis [J] . Zurek Jiri, Kyr Michal, Vavrina Martin, Open medicine . 2015,第1期

机译：三叶因子3作为败血症期间肠道细胞损伤的标志
2. Trefoil factor 3 as a marker of intestinal cell damage during sepsis [J] . Ji?í ?urek, Michal Kyr, Martin Vav?ina, Open medicine . 2015,第1期

机译：三叶因子3作为败血症期间肠道细胞损伤的标志
3. Effect of Sepsis on Mucosal Protein Synthesis in Different Parts of the Gastrointestinal Tract in Rats [J] . Josef E. Fischer, Kenneth Wagner, Per-Olof Hasselgren, Clinical Science . 1994,第2期

机译：败血症对大鼠胃肠道不同部位粘膜蛋白合成的影响
4. Application autofluorescence diagnosis method in endoscopy for investigation mucosal structure in gastrointestinal tract [C] . Larisa Varlamova, Dmitrii Abramov, Arsenii Golovin, Medical applications of laser-generated beams of particles IV: review of progress and strategies for the future . 2017

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5. Evaluation of mucosal damage and recovery in the gastrointestinal tract of rats by penetration enhancers. [D] . Narkar, Yogeeta. 2006

机译：渗透促进剂评估大鼠胃肠道粘膜损伤和恢复。
6. Trefoil factor 3 as a marker of intestinal cell damage during sepsis [O] . Jiří Žurek, Michal Kýr, Martin Vavřina, 2015

机译：三叶因子3作为败血症期间肠道细胞损伤的标志
7. Trefoil factor 3 as a marker of intestinal cell damage during sepsis [O] . Žurek Jiří, Kýr Michal, Vavřina Martin, 2015

机译：三叶因子3作为败血症期间肠细胞损伤的标志物

Trefoil Factor 1 as a marker of mucosal damage of the gastrointestinal tract in children with sepsis

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