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首页> 外文期刊>Bioprocess and Biosystems Engineering >Green approach for synthesis of zinc oxide nanoparticles from Andrographis paniculata leaf extract and evaluation of their antioxidant, anti-diabetic, and anti-inflammatory activities
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Green approach for synthesis of zinc oxide nanoparticles from Andrographis paniculata leaf extract and evaluation of their antioxidant, anti-diabetic, and anti-inflammatory activities

机译：从穿心莲叶提取物中合成氧化锌纳米粒子的绿色方法及其抗氧化，抗糖尿病和抗炎活性的评估

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摘要

Bio-mediated synthesis of zinc oxide nanoparticles (ZnO NPs) was carried out by utilizing the reducing and capping potential of Andrographis paniculata leaf extract. The capped ZnO NPs were characterized using UV-Vis, XRD, FTIR, SEM, TEM and SAED analyses. FTIR analysis suggested the role of phenolic compounds, terpenoids, and proteins of A. paniculata leaf extract, in nucleation and stability of ZnO NPs. XRD pattern compared with the standard confirmed spectrum of zinc oxide particles formed in the present experiments were in the form of nanocrystals, as evidenced by the peaks at 2 theta values. SEM and TEM analysis of ZnO NPs reveals those spherical and hexagonal shapes and the sizes at the range of 96-115 and 57 +/- 0.3 nm, respectively. The synthesized nanoparticles possess strong biological activities regarding anti-oxidant, anti-diabetic, and anti-inflammatory potentials which could be utilized in various biological applications by the cosmetic, food and biomedical industries.
机译：利用穿心莲的叶提取物的还原和封端潜力，进行了生物介导的氧化锌纳米颗粒（ZnO NPs）的合成。使用UV-Vis，XRD，FTIR，SEM，TEM和SAED分析对封端的ZnO NP进行表征。 FTIR分析表明，酚类化合物，萜类化合物和沙枣叶片提取物的蛋白质在ZnO NP的成核和稳定性中起着重要作用。与在本实验中形成的氧化锌颗粒的标准确认光谱相比，XRD图呈纳米晶体形式，如在2θ值处的峰所证明。 ZnO NPs的SEM和TEM分析显示出球形和六边形形状，尺寸分别在96-115和57 +/- 0.3 nm范围内。合成的纳米颗粒具有强大的抗氧化，抗糖尿病和抗发炎的生物活性，可用于化妆品，食品和生物医学行业的各种生物应用中。

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