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Using a flexible shaft agitator to enhance the rheology of a complex fungal fermentation culture

机译:使用柔性轴搅拌器来增强复杂的真菌发酵培养的流变性

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摘要

The rheology behavior of biological fluids particularly when the viscosity is high and rheology is complex, is an important issue to understand, particularly for studies in mass-transfer and for solving technical problems with mixing in stirred bioreactors. In this paper, the use of a Swingstir(A (R)) impeller during the fermentation of Aspergillus oryzae resulted in decreases from the parameters of a power-law model, in viscosity and in the thixotropic behavior of a cultivation broth. The results showed that both the K (L) a and the alpha amylase activity were improved when using the Swingstir(A (R)) in comparison with Fullzone(A (R)) impeller (FZ) at the same level of energy consumption. Increasing the pellet porosity during mixing via the Swingstir(A (R)) resulted in increases in oxygen mass transfer and the average shear stress.
机译:特别是对于传质研究和解决搅拌生物反应器混合中的技术问题,生物流体的流变行为(尤其是当粘度高且流变复杂时)是需要理解的重要问题。在本文中,在米曲霉发酵过程中使用Swingstir(A)叶轮导致幂律模型参数,培养液粘度和触变性降低。结果表明,在相同的能耗水平下,使用Swingstir(A(R))与Fullzone(A(R))叶轮(FZ)相比,K(L)a和α淀粉酶活性均得到改善。通过Swingstir(A(R))在混合过程中增加颗粒的孔隙度会导致氧气质量传递和平均剪切应力的增加。

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